Cutaneous squamous cell carcinoma: from biology to therapy

R Corchado-Cobos, N García-Sancha… - International journal of …, 2020 - mdpi.com
Cutaneous squamous cell carcinoma (CSCC) is the second most frequent cancer in humans
and its incidence continues to rise. Although CSCC usually display a benign clinical …

Cutaneous squamous cell carcinoma: the frontier of cancer immunoprevention

MS Chang, M Azin, S Demehri - Annual Review of Pathology …, 2022 - annualreviews.org
Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer, with its
incidence rising steeply. Immunosuppression is a well-established risk factor for cSCC, and …

Advances in cutaneous squamous cell carcinoma management

C Burns, S Kubicki, QB Nguyen, N Aboul-Fettouh… - Cancers, 2022 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is an increasingly prevalent
and morbid cancer worldwide. Management of this cancer has changed significantly in the …

Advances in cutaneous squamous cell carcinoma

MCG Winge, LN Kellman, K Guo, JY Tang… - Nature Reviews …, 2023 - nature.com
Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

Molecular mechanisms of cutaneous squamous cell carcinoma

ML Hedberg, CT Berry, AS Moshiri, Y Xiang… - International Journal of …, 2022 - mdpi.com
Non-melanoma skin cancers are cutaneous malignancies representing the most common
form of cancer in the United States. They are comprised predominantly of basal cell …

Real-world outcomes treating patients with advanced cutaneous squamous cell carcinoma with immune checkpoint inhibitors (CPI)

GJ Hanna, ES Ruiz, NR LeBoeuf, M Thakuria… - British Journal of …, 2020 - nature.com
Background Immunotherapy has revolutionised the treatment of advanced cutaneous
squamous cell carcinoma (cSCC). It is important to understand both safety and efficacy in a …

Molecular genetics of cutaneous squamous cell carcinoma: perspective for treatment strategies

L Di Nardo, C Pellegrini, A Di Stefani… - Journal of the …, 2020 - Wiley Online Library
Cutaneous squamous cell carcinoma (cSCC) represents 20% of all skin cancers. Although
primary cSCC s can be successfully treated with surgery, a subset of highly aggressive …

Cutaneous squamous cell carcinoma: from pathophysiology to novel therapeutic approaches

L Fania, D Didona, FR Di Pietro, S Verkhovskaia… - Biomedicines, 2021 - mdpi.com
Cutaneous squamous cell carcinoma (cSCC), a non-melanoma skin cancer, is a
keratinocyte carcinoma representing one of the most common cancers with an increasing …

[HTML][HTML] Focus: skin: cutaneous toxicities of immune checkpoint inhibitors: the role of the dermatologist

IW Tattersall, JS Leventhal - The Yale Journal of Biology and …, 2020 - ncbi.nlm.nih.gov
The advent of immune checkpoint inhibition represents a paradigm shift in the treatment of
an increasing number of cancers. However, the incredible therapeutic promise of …

The role of the immune system in cutaneous squamous cell carcinoma

MJ Bottomley, J Thomson, C Harwood… - International journal of …, 2019 - mdpi.com
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. In
immunosuppressed populations it is a source of considerable morbidity and mortality due to …