More and more systematic reviews of diagnostic test accuracy studies are being published,
but they can be methodologically challenging. In this paper, the authors present some of the …

Background: Systematic reviews that “compare” the accuracy of 2 or more tests often include
different sets of studies for each test. Purpose: To investigate the availability of direct …

Meta-analyses of diagnostic test accuracy are uncommon and often based on separate
pooling of sensitivity and specificity, which can lead to biased estimates. Recently, several …

Background: Studies of diagnostic accuracy are subject to different sources of bias and
variation than studies that evaluate the effectiveness of an intervention. Little is known about …

Background: Studies with methodologic shortcomings can overestimate the accuracy of a
medical test. We sought to determine and compare the direction and magnitude of the …

Importance Systematic reviews of diagnostic test accuracy synthesize data from primary
diagnostic studies that have evaluated the accuracy of 1 or more index tests against a …

Objective To classify the sources of bias and variation and to provide an updated summary
of the evidence of the effects of each source of bias and variation. Study Design and Setting …

It is indispensable for any meta‐analysis that potential sources of heterogeneity are
examined, before one considers pooling the results of primary studies into summary …

Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy A guide to
conducting systematic reviews of test accuracy In Cochrane Handbook for Systematic …

A methodological review of how heterogeneity has been examined in systematic reviews of
diagnostic test accuracy. - Abstract - Europe PMC Sign in | Create an account https://orcid.org …