Cytokines are critical for initiating, mediating and resolving the immune response.
Macrophages are key cytokine-secreting cells that can express both pro-and anti …

Ascorbate (vitamin C) is an essential micronutrient in humans. The chronic severe deficiency
of ascorbate, termed scurvy, has long been associated with increased susceptibility to …

Ascorbate (vitamin C) is an essential micronutrient in humans. The severe chronic deficiency
of ascorbate, termed scurvy, has long been associated with increased susceptibility to …

To determine whether macrophage differentiation involves increased uptake of vitamin C, or
ascorbic acid, we assessed the expression and function of its transporter SVCT2 during …

Ascorbate (vitamin C) is an essential micronutrient in humans. The chronic severe deficiency
of ascorbate, termed scurvy, has long been associated with increased susceptibility to …

Tumour-associated macrophages (TAMs) are ubiquitously present in tumours and
commonly associated with poor prognosis. In immune cells, ascorbate affects epigenetic …

Vitamin C (ascorbate) is maintained at high levels in most immune cells and can affect many
aspects of the immune response. Intracellular levels generally respond to variations in …

Immune cells contain high concentrations of vitamin C (ascorbate), which indicates an
important role in immune function. In the intracellular environment, an important function of …

Plasma cells provide high-affinity antibodies against invading pathogens. Although
transcriptional and epigenetic mechanisms have been extensively studied for plasma cell …

Abstract β-Carotene is converted into vitamin A in the body and can remove reactive oxygen
species. However, it is still unclear whether β-carotene alters the expression levels of …