Sirolimus therapy restores the PD-1+ ICOS+ Tfh: CD45RA-Foxp3high activated Tfr cell balance in primary Sjögren's syndrome
Y Wang, H Guo, Z Liang, M Feng, Y Wu, Y Qin… - Molecular …, 2022 - Elsevier
Abstract Background Primary Sjögren's syndrome (pSS) is a common chronic autoimmune
disease characterized by lymphocytic infiltration of salivary and lacrimal glands. The current …
disease characterized by lymphocytic infiltration of salivary and lacrimal glands. The current …
Follicular helper T cells and follicular regulatory T cells in the immunopathology of primary Sjögren's syndrome
W Chen, F Yang, G Xu, J Ma, J Lin - Journal of Leucocyte …, 2021 - academic.oup.com
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease, characterized by
lymphocytic infiltration into exocrine glands, which causes dry eyes, dry mouth, and systemic …
lymphocytic infiltration into exocrine glands, which causes dry eyes, dry mouth, and systemic …
CCR9/CXCR5 Co-Expressing CD4 T Cells Are Increased in Primary Sjögren's Syndrome and Are Enriched in PD-1/ICOS-Expressing Effector T Cells
AC Hinrichs, AA Kruize, FPJG Lafeber… - International Journal of …, 2023 - mdpi.com
Primary Sjögren's syndrome (pSS) is an autoimmune disease characterised by B cell
hyperactivity. CXCR5+ follicular helper T cells (Tfh), CXCR5-PD-1hi peripheral helper T …
hyperactivity. CXCR5+ follicular helper T cells (Tfh), CXCR5-PD-1hi peripheral helper T …
T follicular‐like helper cells in the peripheral blood of patients with primary Sjögren's syndrome
KA Brokstad, M Fredriksen, F Zhou… - Scandinavian …, 2018 - Wiley Online Library
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease characterized by
exocrine gland dysfunction, mainly causing sicca symptoms. B cells have a prominent role in …
exocrine gland dysfunction, mainly causing sicca symptoms. B cells have a prominent role in …
The imbalance of circulating follicular T helper cell subsets in primary Sjögren's syndrome associates with serological alterations and abnormal B-cell distribution
Since B-cell hyperactivity and pathologic antibody response are key features in the
immunopathogenesis of primary Sjögren's syndrome (pSS), the role of follicular T helper …
immunopathogenesis of primary Sjögren's syndrome (pSS), the role of follicular T helper …
[HTML][HTML] Circulating CCR7loPD-1hi follicular helper T cells indicate disease activity and glandular inflammation in patients with primary Sjögren's syndrome
JW Kim, J Lee, SM Hong, J Lee, ML Cho… - Immune …, 2019 - ncbi.nlm.nih.gov
Since primary Sjögren's syndrome (pSS) is an autoummune disease of B cell hyperactivity
and pathologic autoantibody response, follicular helper T (Tfh) cells and follicular regulatory …
and pathologic autoantibody response, follicular helper T (Tfh) cells and follicular regulatory …
Association between T follicular helper cells and T peripheral helper cells with B-cell biomarkers and disease activity in primary Sjögren syndrome
A Dupré, J Pascaud, E Rivière, A Paoletti, B Ly… - RMD open, 2021 - rmdopen.bmj.com
INTRODUCTION Primary Sjögren syndrome (pSS) is a systemic autoimmune disease,
characterised by an infiltration of the exocrine glands, leading to sicca syndrome …
characterised by an infiltration of the exocrine glands, leading to sicca syndrome …
B cell depletion therapy normalizes circulating follicular Th cells in primary Sjögren syndrome
GM Verstappen, FGM Kroese, PM Meiners… - The Journal of …, 2017 - jrheum.org
Objective. To assess the effect of B cell depletion therapy on effector CD4+ T cell
homeostasis and its relation to objective measures of disease activity in patients with …
homeostasis and its relation to objective measures of disease activity in patients with …
Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma
Objectives To explore the relevance of T-follicular-helper (Tfh) and pathogenic peripheral-
helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa …
helper T-cells (Tph) in promoting ectopic lymphoid structures (ELS) and B-cell mucosa …
Follicular helper T cells may play an important role in the severity of primary Sjögren's syndrome
The aim of this study was to investigate the possible role of follicular helper T (TFH) cells in
the pathogenesis of primary Sjögren's syndrome (pSS) by analyzing immune-competent …
the pathogenesis of primary Sjögren's syndrome (pSS) by analyzing immune-competent …