Tetrandrine: a review of its anticancer potentials, clinical settings, pharmacokinetics and drug delivery systems

F Luan, X He, N Zeng - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives Tetrandrine, a natural bisbenzylisoquinoline alkaloid, possesses promising
anticancer activities on diverse tumours. This review provides systematically organized …

[HTML][HTML] Tetrandrine, a Chinese plant-derived alkaloid, is a potential candidate for cancer chemotherapy

T Liu, X Liu, W Li - Oncotarget, 2016 - ncbi.nlm.nih.gov
Cancer is a disease caused by the abnormal proliferation and differentiation of cells
governed by tumorigenic factors. Chemotherapy is one of the major cancer treatment …

[PDF][PDF] Potential role of tetrandrine in cancer therapy

C Yu-Jen - Acta Pharmacol. Sin, 2002 - Citeseer
Tetrandrine, a bisbenylisoquinoline alkaloid isolated from the dried root of Stephenia
tetrandra S Moore, exhibits very broad pharmacological actions, including anti-tumor activity …

[HTML][HTML] Tetrandrine and cancer–An overview on the molecular approach

N Bhagya, KR Chandrashekar - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Tetrandrine has been known in the treatment of tuberculosis, hyperglycemia, negative
ionotropic and chronotropic effects on myocardium, malaria, cancer and fever since years …

Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells

XY Bai, YG Liu, W Song, YY Li, DS Hou… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives To investigate the antitumour property of tetrandrine by inducing autophagy and
apoptosis in human gastric cancer cells, and to explore the potential molecular mechanisms …

Tetrandrine inhibits colon carcinoma HT-29 cells growth via the Bcl-2/Caspase 3/PARP pathway and G1/S phase

JN Li, QH Wang, ZB Wang, N Cui, BY Yang… - Bioscience …, 2019 - portlandpress.com
Tetrandrine (Tet) bisbenzylisoquinoline alkaloids isolated from Stephania tetrandra and
other related species of Menispermaceae. It has been demonstrated to have positive …

Prospects of tangeretin as a modulator of cancer targets/pathways

W Raza, S Luqman, A Meena - Pharmacological Research, 2020 - Elsevier
To date, cancer is the second leading cause of death worldwide after cardiac arrest. A large
number of synthetic drugs are available for the treatment of different types of cancer; …

[HTML][HTML] Autophagy and cancer: Can tetrandrine be a potent anticancer drug in the near future?

N Bhagya, KR Chandrashekar - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Autophagy is an essential catabolic process in mammalian cells to maintain cellular integrity
and viability by degrading the old and damaged cell organelles and other contents with the …

Tectorigenin: A review of its sources, pharmacology, toxicity, and pharmacokinetics

J Rong, F Fu, C Han, Y Wu, Q Xia, D Du - Molecules, 2023 - mdpi.com
Tectorigenin is a well-known natural flavonoid aglycone and an active component that exists
in numerous plants. Growing evidence suggests that tectorigenin has multiple …

Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats

Y Chen, JC Chen, SH Tseng - International journal of cancer, 2009 - Wiley Online Library
Tetrandrine, a bisbenzylisoquinoline alkaloid, has antitumor effects against some cancers,
but its effects on gliomas are unknown. In this study, we investigated the effects of …