Effect of FDA investigation on opioid prescribing to children after tonsillectomy/adenoidectomy

KP Chua, MG Shrime, RM Conti - Pediatrics, 2017 - publications.aap.org
BACKGROUND: In August 2012, the Food and Drug Administration investigated the safety
of codeine use by children after tonsillectomy and/or adenoidectomy, culminating in a black …

Continued prescribing of periprocedural codeine and tramadol to children after a black box warning

JE Kohler, RS Cartmill, E Kalbfell… - Journal of Surgical …, 2020 - Elsevier
Background Codeine and tramadol are commonly used analgesics in surgery. In 2013, the
Food and Drug Administration (FDA) issued a contraindication to the use of codeine in …

Otolaryngology practice patterns in pediatric tonsillectomy: the impact of the codeine boxed warning

JL Goldman, C Ziegler, EM Burckardt - The Laryngoscope, 2018 - Wiley Online Library
Objectives/Hypothesis To determine if otolaryngologists at a single children's hospital were
adherent to the boxed warning for codeine use in post‐tonsillectomy patients and the …

Association of perioperative opioid prescriptions with risk of complications after tonsillectomy in children

KP Chua, CM Harbaugh, CM Brummett… - … –Head & Neck …, 2019 - jamanetwork.com
Importance Practice guidelines recommend nonopioid medications in children after
tonsillectomy, but to date, studies have not used recent national data to assess perioperative …

What is the best non‐codeine postadenotonsillectomy pain management for children?

RF Yellon, MA Kenna, FP Cladis, W Mcghee… - The …, 2014 - Wiley Online Library
BACKGROUND Concern regarding codeine use following adenotonsillectomy in children
has increased following warnings from the Food and Drug Administration (FDA) of deaths …

Patterns of dispensed opioids after tonsillectomy in children and adolescents in South Carolina, United States, 2010–2017

WT Basco Jr, RC Ward, DJ Taber, KN Simpson… - International journal of …, 2021 - Elsevier
Objectives Tonsillectomy (with or without adenoidectomy) is a common pediatric surgical
procedure requiring post-operative analgesia. Because of the respiratory depression effects …

Codeine‐related adverse drug reactions in children following tonsillectomy: a prospective study

CA Prows, X Zhang, MM Huth, K Zhang… - The …, 2014 - Wiley Online Library
Objectives/Hypothesis To prospectively determine factors associated with codeine's adverse
drug reactions (ADRs) at home in a large homogenous population of children undergoing …

FDA: No codeine after tonsillectomy for children

BM Kuehn - Jama, 2013 - jamanetwork.com
PHYSICIANS SHOULD NOT USE CO-deine to treat pain in children after tonsillectomy or
adenoidectomy, warns the US Food and Drug Administration (FDA)(http://tinyurl …

Opioid prescribing patterns following pediatric tonsillectomy in the United States, 2009–2017

ZJ Qian, JC Alyono, MC Jin, SP Cooperman… - The …, 2021 - Wiley Online Library
Objectives Assess national trends in opioid prescription following pediatric tonsillectomy: 1)
overall percentage receiving opioids and mean quantity, 2) changes during 2009–2017, and …

Is it farewell to codeine?

BJ Anderson - Archives of Disease in Childhood, 2013 - adc.bmj.com
Codeine was considered a suitable analgesic for children after adenotonsillectomy. It has
been used extensively in the UK1 for over 40 years and appeared effective. 2 It was listed in …