[HTML][HTML] Dihydroquercetin supplementation improved hepatic lipid dysmetabolism mediated by gut microbiota in high-fat diet (HFD)-fed mice

M Wang, H Han, F Wan, R Zhong, YJ Do, SI Oh, X Lu… - Nutrients, 2022 - mdpi.com
Dihydroquercetin (DHQ) is a natural flavonoid with multiple bioactivities, including
hepatoprotective effects. This study aimed to investigate whether DHQ improved lipid …

Quercetin improves high‐fat diet‐induced obesity by modulating gut microbiota and metabolites in C57BL/6J mice

L Su, Y Zeng, G Li, J Chen, X Chen - Phytotherapy Research, 2022 - Wiley Online Library
High‐fat diet‐induced obesity is characterized by low‐grade inflammation, which has been
linked to gut microbiota dysbiosis. We hypothesized that quercetin supplementation would …

Structural insights into amelioration effects of quercetin and its glycoside derivatives on NAFLD in mice by modulating the gut microbiota and host metabolism

Z Shi, C Zhang, H Lei, C Chen, Z Cao… - Journal of Agricultural …, 2022 - ACS Publications
The sugar moieties of natural flavonoids determine their absorption, bioavailability, and
bioactivity in humans. To explore structure-dependent bioactivities of quercetin …

Analysis of the mechanism of action of quercetin in the treatment of hyperlipidemia based on metabolomics and intestinal flora

T Wang, L Liu, J Deng, Y Jiang, X Yan, W Liu - Food & function, 2023 - pubs.rsc.org
Hyperlipidemia (HLP) is one of the main factors leading to cardiovascular diseases.
Quercetin (QUE) is a naturally occurring polyhydroxy flavonoid compound that has a wide …

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related …

D Porras, E Nistal, S Martínez-Flórez… - Free Radical Biology …, 2017 - Elsevier
Gut microbiota is involved in obesity, metabolic syndrome and the progression of
nonalcoholic fatty liver disease (NAFLD). It has been recently suggested that the flavonoid …

Plasma quercetin metabolites are affected by intestinal microbiota of human microbiota-associated mice fed with a quercetin-containing diet

M Tamura, H Nakagawa, S Hori, T Suzuki… - Journal of Clinical …, 2019 - jstage.jst.go.jp
Copyright Đ 2019 JCBN 2019This is an open access article distributed under the terms of
the Creative Commons Attribution License, which permits unre-stricted use, distribution, and …

[HTML][HTML] Quercetin ameliorates insulin resistance and restores gut microbiome in mice on high-fat diets

Y Tan, CC Tam, M Rolston, P Alves, L Chen, S Meng… - Antioxidants, 2021 - mdpi.com
Quercetin is a flavonoid that has been shown to have health-promoting capacities due to its
potent antioxidant activity. However, the effect of chronic intake of quercetin on the gut …

Tea polyphenol and epigallocatechin gallate ameliorate hyperlipidemia via regulating liver metabolism and remodeling gut microbiota

JJ Wen, MZ Li, CH Chen, T Hong, JR Yang, XJ Huang… - Food Chemistry, 2023 - Elsevier
Hyperlipidemia can directly cause metabolic diseases that seriously endanger disorder and
metabolism and gut health. Tea polyphenol (TP) and epigallocatechin gallate (EGCG) was …

[HTML][HTML] Quercetin Alleviates Insulin Resistance and Repairs Intestinal Barrier in db/db Mice by Modulating Gut Microbiota

M Yuan, T Sun, Y Zhang, C Guo, F Wang, Z Yao, L Yu - Nutrients, 2024 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease which seriously affects
public health. Gut microbiota remains a dynamic balance state in healthy individuals, and its …

Heptamethoxyflavone alleviates metabolic syndrome in high-fat diet-fed mice by regulating the composition, function, and metabolism of gut microbiota

K Feng, H Zhang, C Chen, CT Ho, M Kang… - Journal of agricultural …, 2023 - ACS Publications
3, 5, 6, 7, 8, 3′, 4′-Heptamethoxyflavone (HMF) could prevent obesity and hyperlipidemia,
but its effects on gut microbiota and fecal metabolites remain unclear. Here, the effect of …