Microfluidic systems in extracellular vesicles single analysis. A systematic review

FG Ortega-Sanchez, V Teresa, T Widmann… - TrAC Trends in …, 2023 - Elsevier
Extracellular vesicles (EVs) are key elements in cell-to-cell communication and important
circulating carriers of molecular biomarkers. There is an increasing interest in the analysis of …

Advanced microfluidic technologies for isolating extracellular vesicles

S Zhang, J Deng, J Li, F Tian, C Liu, L Fang… - TrAC Trends in Analytical …, 2022 - Elsevier
Extracellular vesicles (EVs) are lipid membrane-enclosed, cell-secreted nanovesicles that
have attracted significant attentions in recent years in view of their potential as non-invasive …

Single-cell extracellular vesicle analysis by microfluidics and beyond

G Wu, Y Zhao, X Li, MM Ali, S Jia, Y Ren… - TrAC Trends in Analytical …, 2023 - Elsevier
Extracellular vesicles (EVs) are membrane vesicles encapsulated by lipid membranes
present in most body fluids. These EVs contain abundant biomolecular composition …

From conventional to microfluidic: progress in extracellular vesicle separation and individual characterization

M Chen, S Lin, C Zhou, D Cui, H Haick… - Advanced Healthcare …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are nanoscale membrane vesicles, which contain a wide variety
of cargo such as proteins, miRNAs, and lipids. A growing body of evidence suggests that …

[HTML][HTML] Advancement and obstacles in microfluidics-based isolation of extracellular vesicles

M Havers, A Broman, A Lenshof, T Laurell - Analytical and Bioanalytical …, 2023 - Springer
There is a great need for techniques which enable reproducible separation of extracellular
vesicles (EVs) from biofluids with high recovery, purity and throughput. The development of …

Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions

S Gholizadeh, MS Draz, M Zarghooni… - Biosensors and …, 2017 - Elsevier
Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …

A modular microfluidic platform for serial enrichment and harvest of pure extracellular vesicles

H Gwak, S Park, H Yu, KA Hyun, HI Jung - Analyst, 2022 - pubs.rsc.org
Extracellular vesicles (EVs) are recognized as promising biomarkers for several diseases.
However, their conventional isolation methods have several drawbacks, such as poor yields …

Advances in microfluidic extracellular vesicle analysis for cancer diagnostics

S Cheng, Y Li, H Yan, Y Wen, X Zhou, L Friedman… - Lab on a Chip, 2021 - pubs.rsc.org
Extracellular vesicles (EVs) secreted by cells into the bloodstream and other bodily fluids,
including exosomes, have been demonstrated to be a class of significant messengers that …

[HTML][HTML] Microfluidic strategies for Extracellular Vesicle isolation: towards clinical applications

A Meggiolaro, V Moccia, P Brun, M Pierno, G Mistura… - Biosensors, 2022 - mdpi.com
Extracellular vesicles (EVs) are double-layered lipid membrane vesicles released by cells.
Currently, EVs are attracting a lot of attention in the biological and medical fields due to their …

[HTML][HTML] Advances in the analysis of single extracellular vesicles: A critical review

SH Hilton, IM White - Sensors and actuators reports, 2021 - Elsevier
There is an ever-growing need for new cancer diagnostic approaches that provide earlier
diagnosis as well as richer diagnostic, prognostic, and resistance information. Extracellular …