After implantation of a biomaterial, both the host immune system and properties of the
material determine the local immune response. Through triggering or modulating the local …

Biomaterials are defined as “engineered materials” and include a range of natural and
synthetic products, designed for their introduction into and interaction with living tissues …

The immune system plays a crucial role during tissue repair and wound healing processes.
Biomaterials have been leveraged to assist in this in situ tissue regeneration process to …

The foreign body response (FBR) caused by biomaterials can essentially be understood as
the interaction between the immune microenvironment and biomaterials, which has severely …

The immune system has evolved to recognize and eliminate pathogens; this recognition
relies on the identification of structural molecular patterns within unique tissue …

All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Objectives Biomaterials are routinely used in clinical applications. A key to the clinical
success of implanted biomaterials is not eliciting detrimental immune responses. In this …

Implantable biomaterials represent the forefront of regenerative medicine, providing
platforms and vessels for delivering a creative range of therapeutic benefits in diverse …

The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …

Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …