Harnessing the therapeutic potential of extracellular vesicles for biomedical applications using multifunctional magnetic nanomaterials

L Yang, KD Patel, C Rathnam, R Thangam, Y Hou… - Small, 2022 - Wiley Online Library
Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Targeted extracellular vesicle delivery systems employing superparamagnetic iron oxide nanoparticles

Z Zhuo, J Wang, Y Luo, R Zeng, C Zhang, W Zhou… - Acta biomaterialia, 2021 - Elsevier
In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …

Blood exosomes endowed with magnetic and targeting properties for cancer therapy

H Qi, C Liu, L Long, Y Ren, S Zhang, X Chang, X Qian… - ACS …, 2016 - ACS Publications
Exosomes are a class of naturally occurring nanoparticles that are secreted endogenously
by mammalian cells. Clinical applications for exosomes remain a challenge because of their …

Cell-derived vesicles as a bioplatform for the encapsulation of theranostic nanomaterials

AKA Silva, R Di Corato, T Pellegrino, S Chat… - Nanoscale, 2013 - pubs.rsc.org
There is a great deal of interest in the development of nanoplatforms gathering versatility
and multifunctionality. The strategy reported herein meets these requirements and further …

Immuno-modified superparamagnetic nanoparticles via host–guest interactions for high-purity capture and mild release of exosomes

S Cai, B Luo, P Jiang, X Zhou, F Lan, Q Yi, Y Wu - Nanoscale, 2018 - pubs.rsc.org
The study of exosomes has great significance for cancer diagnosis and prognosis, in which
damage-free isolation of exosomes is a critically important step due to their extremely low …

A magnetic bead-mediated selective adsorption strategy for extracellular vesicle separation and purification

X Fang, C Chen, B Liu, Z Ma, F Hu, H Li, H Gu, H Xu - Acta biomaterialia, 2021 - Elsevier
Extracellular vesicles (EVs) are membrane-encapsulated particles with critical biomedical
functions, including mediating intercellular communication, assisting tumor metastasis, and …

Tracking exosomes in vitro and in vivo to elucidate their physiological functions: implications for diagnostic and therapeutic nanocarriers

LM Shen, L Quan, J Liu - ACS Applied Nano Materials, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) secreted by a variety of cell types and
widely distributed in body fluids. With a lipid-bilayer membrane encapsulating genetic and …

Magnetic and folate functionalization enables rapid isolation and enhanced tumor-targeting of cell-derived microvesicles

W Zhang, ZL Yu, M Wu, JG Ren, HF Xia, GL Sa… - Acs Nano, 2017 - ACS Publications
Cell-derived microvesicles (MVs), which are biogenic nanosized membrane-bound vesicles
that convey bioactive molecules between cells, have recently received attention for use as …

Extracellular vesicles: A bright star of nanomedicine

P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

A perspective on the isolation and characterization of extracellular vesicles from different biofluids

R Bano, F Ahmad, M Mohsin - RSC advances, 2021 - pubs.rsc.org
Extracellular vesicles (EVs) are small membrane-bound particles, which include exosomes,
micro vesicles (MVs) and various-sized vesicles, released by healthy and diseased cells …