Abstract α7-nAChR is a nicotinic acetylcholine receptor [specifically expressed on hepatic
stellate cells (HSCs), Kupffer cells, and cholangiocytes] that regulates inflammation and …

Background Activation of alpha-7 nicotinic acetylcholine receptor (α7nAChR) can inhibit a
systemic inflammatory response and preserve intestinal barrier integrity. This study aimed at …

Background Cholangiocarcinoma is one of the most deadly malignant tumors characterized
by a tendency of local invasiveness and metastasis at the early phase, high recurrence rate …

The cholinergic signaling pathways have been recently implicated in the development of
various human cancers. However, the underlying molecular mechanism remains largely …

Nicotine, the main addictive substance in tobacco, is known to play a role in the
development and/or progression of a number of malignant tumors. However, nicotine's …

Objective Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases
worldwide; yet, the pathogenesis of the disorder is not completely understood. The nicotinic …

Alpha7 nicotinic acetylcholine receptor (α7nAChR) has been reported to be protective in
several kinds of disorders through inflammatory suppression. Here, we investigated the role …

Alpha7 nicotinic acetylcholine receptor (α7nAChR) is one of the main subtypes of nAChRs
that modulates various cancer-related properties including proliferative, anti-apoptotic, pro …

Activation of the cholinergic anti-inflammatory pathway (CAP) via vagus nerve stimulation
has been shown to improve acute kidney injury in rodent models. While alpha 7 nicotinic …

Background: Hepatocellular carcinoma (HCC) is a worldwide health problem. Currently,
there is no effective clinical therapeutic strategy for HCC. Smoking is associated with several …