Galanin receptors and ligands

KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …

Galanin receptor subtypes and ligand binding

A Florén, T Land, Ü Langel - Neuropeptides, 2000 - Elsevier
Galanin is a neuropeptide initiating its multiple biological effects by binding to different
subtypes of seven transmembrane spanning galanin receptors, thus transducing the …

The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease

R Lang, AL Gundlach, B Kofler - Pharmacology & therapeutics, 2007 - Elsevier
The galanin peptide family consists of the “parental” galanin, galanin-message-associated
peptide (GMAP) which derives from the same peptide precursor gene product as galanin …

Galanin–25 years with a multitalented neuropeptide: Galanin, galanin receptors and drug targets

K Mitsukawa, X Lu, T Bartfai - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin, a neuropeptide widely expressed in the central and peripheral nervous systems
and in the endocrine system, has been shown to regulate numerous physiological and …

Galanin receptor ligands

X Lu, L Lundström, U Langel, T Bartfai - Neuropeptides, 2005 - Elsevier
The three galanin receptor subtypes (GalR1–3) belong to the G protein-coupled receptor
superfamily. The widespread distribution of galanin and its receptors in the CNS and PNS …

Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Galanin (2–11) binds to GalR3 in transfected cell lines: limitations for pharmacological definition of receptor subtypes

X Lu, L Lundström, T Bartfai - Neuropeptides, 2005 - Elsevier
The neuropeptide galanin regulates a variety of physiological and pathophysiological
processes through three G protein coupled receptors, GalR1, GalR2, and GalR3. The …

Galanin receptor subtypes

TA Branchek, KE Smith, C Gerald… - Trends in pharmacological …, 2000 - cell.com
The neuropeptide galanin, which is widely expressed in brain and peripheral tissues, exerts
a broad range of physiological effects. Pharmacological studies using peptide analogues …

M871—a novel peptide antagonist selectively recognizing the galanin receptor type 2

UE Sollenberg, L Lundström, T Bartfai… - International Journal of …, 2006 - Springer
Galanin and its three receptors have been linked to a wide variety of physiological
processes and are distributed in both the central and peripheral nervous systems. Further …

Galanin–25 years with a multitalented neuropeptide: Galanin and the neuroendocrine axes

I Mechenthaler - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin has diverse physiological functions, including nociception, arousal/sleep regulation,
cognition, and many aspects of neuroendocrine activities that are associated with feeding …