The mainstay of therapy of chronic lymphocytic leukemia (CLL) is cytotoxic chemotherapy;
however, CLL is still an incurable disease with resistance to therapy developing in the …

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in Western
countries and is characterized by the clonal expansion of mature CD5+ B cells. There have …

Significant advancements in the care of patients with chronic lymphocytic leukemia (CLL)
have occurred over the past decade. Nonetheless, CLL remains incurable outside of …

In recent years, our understanding of the pathophysiology of chronic lymphocytic leukemia
(CLL) has advanced significantly. It is now clear that CLL is a relatively proliferative disorder …

Despite significant progress in treatment, chronic lymphocytic leukemia (CLL) remains an
incurable disease. Advances have been made to understand the molecular pathogenesis …

Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion of CD5+
CD23+ B cells in blood, marrow, and second lymphoid tissues. Gene-expression profiling …

Chronic lymphocytic leukaemia (CLL) has several unique features that distinguish it from
other cancers. Most CLL tumour cells are inert and arrested in G0/G1 of the cell cycle and …

Chronic lymphocytic leukemia (CLL) has unique epidemiologic, biologic, and clinical
features. The progressively emerging picture leads us to consider that the critical genes for …

B-cell chronic lymphocytic leukemia (CLL) is caused by the abnormal accumulation of non-
functional B-cells in peripheral blood and bone marrow. However, the precise aetiology and …

Chronic lymphocytic leukaemia (CLL), the most frequent type of leukaemia in adults, is a
lymphoproliferative disorder that is characterized by the expansion of monoclonal, mature …