Neuroimmunology as a separate discipline has its roots in the fields of neurology,
neuroscience and immunology. Early studies of the brain by Golgi and Cajal, the detailed …

Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …

The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

The pathophysiology of complex neuroimmunological diseases, such as multiple sclerosis
and autoimmune encephalitis, remains puzzling—various mechanisms that are difficult to …

The brain is an immune-privileged organ such that immune cell infiltration is highly
regulated and better tolerating the introduction of antigen to reduce risk of harmful …

The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …

Neurodegenerative diseases, the leading cause of morbidity and disability, are gaining
increased attention as they impose a considerable socioeconomic impact, due in part to the …

While immune responses in neurodegeneration were regarded as little more than a curiosity
a decade ago, they are now increasingly moving toward center stage. Factors driving this …

Mounting evidence suggests that the nervous and immune systems are intricately linked.
Many proteins first identified in the immune system have since been detected at synapses …

Immune cells rely on cell-cell communication to specify and fine-tune their responses. They
express an extensive network of cell communication modes, including a vast repertoire of …