[HTML][HTML] Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Oxidative stress and pathophysiology of ischemic stroke: novel therapeutic opportunities

R Rodrigo, R Fernandez-Gajardo… - CNS & Neurological …, 2013 - ingentaconnect.com
Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …

[HTML][HTML] Targeting oxidative stress and inflammation to prevent ischemia-reperfusion injury

L Wu, X Xiong, X Wu, Y Ye, Z Jian, Z Zhi… - Frontiers in molecular …, 2020 - frontiersin.org
The cerebral ischemia injury can result in neuronal death and/or functional impairment,
which leads to further damage and dysfunction after recovery of blood supply. Cerebral …

Oxidative stress–assassin behind the ischemic stroke

H Pradeep, JB Diya, S Shashikumar… - Folia …, 2012 - termedia.pl
Ischemic stroke is the second leading cause of death and disability worldwide and is
associated with significant clinical and socioeconomic implications, emphasizing the need …

Pathogenic mechanisms following ischemic stroke

SE Khoshnam, W Winlow, M Farzaneh, Y Farbood… - Neurological …, 2017 - Springer
Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

[HTML][HTML] The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke

S Kim, W Lee, H Jo, SK Sonn, SJ Jeong, S Seo, J Suh… - Redox biology, 2022 - Elsevier
Ischemic stroke is the leading cause of immortal disability and death worldwide. For
treatment in the acute phase, it is necessary to control excessive reactive oxygen species …

[HTML][HTML] Inflammatory mechanisms in ischemic stroke: therapeutic approaches

SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury

S Manzanero, T Santro, TV Arumugam - Neurochemistry international, 2013 - Elsevier
Oxidative stress has emerged as a key deleterious factor in brain ischemia and reperfusion.
Malfunction of the oxidative respiratory chain in mitochondria combines with the activation of …

[HTML][HTML] Neuroinflammation: friend and foe for ischemic stroke

RL Jayaraj, S Azimullah, R Beiram, FY Jalal… - Journal of …, 2019 - Springer
Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology

H Chen, Y He, S Chen, S Qi, J Shen - Pharmacological Research, 2020 - Elsevier
Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …