[HTML][HTML] Standardised Sonneratia apetala Buch.-Ham. fruit extract inhibits human neutrophil elastase and attenuates elastase-induced lung injury in mice

S Sengupta, N Abhinav, S Singh, J Dutta… - Frontiers in …, 2022 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) along with asthma is a major and increasing
global health problem. Smoking contributes to about 80%–90% of total COPD cases in the …

[PDF][PDF] Phenolic compounds from medicinal plants as natural anti-elastase products for the therapy of pulmonary emphysema

R Kacem - J Med Plants Res, 2013 - academicjournals.org
Medicinal plants have been used as alternative treatments to health problems. Most of the
natural remedies are based on medicinal plants. Many reports have demonstrated that the …

Effects of Alchornea cordifolia on elastase and superoxide anion produced by human neutrophils

G Kouakou-Siransy, S Sahpaz… - Pharmaceutical …, 2010 - Taylor & Francis
The ability of Alchornea cordifolia (Schum. and Thonn.) Müll. Arg.(Euphorbiaceae) leaves to
inhibit human neutrophil elastase (HNE) and superoxide anion (O2•–) activities was …

Human neutrophil elastase inhibitory potential of flavonoids from Campylotropis hirtella and their kinetics

XF Tan, DW Kim, YH Song, JY Kim, HJ Yuk… - Journal of Enzyme …, 2016 - Taylor & Francis
Campylotropis hirtella is used as a food supplement in the subtropical region of China. In an
intensive hunt for human neutrophil elastase inhibitors, we isolated eight flavonoids from C …

The effect of sesquiterpene lactones on the release of human neutrophil elastase

B Siedle, L Gustavsson, S Johansson, R Murillo… - Biochemical …, 2003 - Elsevier
Sesquiterpene lactones (SLs) are natural products responsible for the anti-inflammatory
activity of a variety of medicinal plants, mainly from the Asteraceae family. Here, we …

[PDF][PDF] Human neutrophil elastase inhibitory alkaloids from Chelidonium majus L

JY Kim, JH Lee, YH Song, WM Jeong, X Tan… - J. Appl. Biol …, 2015 - academia.edu
Human neutrophil elastase (HNE) represents a good therapeutic target for the treatment of
inflammatory diseases as well as invasion of microorganism. The methanol extract of a …

[PDF][PDF] Preferential inhibition of bacterial elastase over human neutrophil elastase by leaf extracts of Psidium guajava: an in vitro study

D Mendez, AVM Kutty, SR Prasad - National Journal of Physiology …, 2016 - njppp.com
|| ABSTRACT Background: The guava (Psidium guajava), belonging to family Myrtaceae, is
a small tree grown widely for its fruit in tropical and subtropical countries. Apart from its …

Triterpenoids as neutrophil elastase inhibitors

D Guillaume, TNT Huynh, C Denhez… - Natural Product …, 2015 - journals.sagepub.com
Neutrophile elastase has the capacity to degrade elastin, a protein found in the connective
tissue of the lungs. Unchecked elastase leads to pulmonary pathologies. Therefore, the …

[HTML][HTML] Inhibition of human neutrophil elastase by pentacyclic triterpenes

L Feng, X Liu, W Zhu, F Guo, YingchunWu, R Wang… - PLoS …, 2013 - journals.plos.org
Scope Inhibiting human neutrophil elastase (HNE) is a promising strategy for treating
inflammatory lung diseases, such as H1N1 and SARS virus infections. The use of sivelestat …

New coumarins isolated from the stem bark of Fraxinus rhynchophylla inhibit human neutrophil elastase and LPS-induced inflammation in RAW 264.7 cells

BZ Lee, KM Kim, S Chae, SK Jeong, S Lee… - Phytochemistry …, 2020 - Elsevier
Abstract Two new coumarins (1 and 2), together with six known compounds (3–8), were
isolated from the stem bark of Fraxinus rhynchophylla. The structures of these compounds …