Integrin αvβ3 plays a significant role in tumor angiogenesis and is a receptor for the
extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide …

Integrin αvβ3 plays a significant role in tumor angiogenesis and is a receptor for the
extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide …

The integrin family comprises 24 transmembrane receptors, each a heterodimeric
combination of one of 18α and one of 8β subunits. Their main function is to integrate the cell …

Angiogenesis is a requirement for tumor growth and metastasis. The angiogenic process
depends on vascular endothelial cell migration and invasion, and is regulated by various …

The αvβ3 integrin plays a pivotal role in angiogenesis and tumor metastasis. Angiogenic
blood vessels overexpress αvβ3 integrin, as in tumor neovascularization, and αvβ3 integrin …

Three amino acids residues, Arg-Gly-Asp (RGD), in vitronectin and fibronectin show affinity
for αVβ3 integrins expressed in vascular endothelial cells. That tumor growth can upregulate …

Integrin αvβ3 plays a critical role in tumor angiogenesis and metastasis. Suitably
radiolabeled cyclic arginine-glycine-aspartic (RGD) peptides can be used for noninvasive …

The αVβ3 integrin plays an important role in metastasis and tumor-induced angiogenesis.
Targeting with radiolabeled ligands of the αVβ3 integrin may provide information about the …

Abstract Purpose Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides have great potential for
the early tumor detection and noninvasive monitoring of tumor metastasis and therapeutic …

The αvβ3 integrin, a transmembrane heterodimeric protein expressed on sprouting
endothelial cells, binds to the arginine-glycine-aspartic acid (RGD) amino acid sequence of …