The outer membrane of Gram‐negative bacteria is a crucial permeability barrier allowing the
cells to survive a myriad of toxic compounds, including many antibiotics. This innate form of …

Gram-negative bacteria can resist antibiotics by changing the permeability via their outer
membrane. These bacteria have a complex cell envelope that incorporates an outer …

The outer membrane is a distinguishing feature of the Gram-negative envelope. It lies on the
external face of the peptidoglycan sacculus and forms a robust permeability barrier that …

Publisher Summary Cohn suggested that the resistance of bacteria to attack by acids and
alkalies was because of the presence of a rigid structure surrounding the cell. The …

An important question for bacterial cell division is how the invaginating septum can
overcome the turgor force generated by the high osmolarity of the cytoplasm. I suggest that it …

The global increase in multi-drug-resistant bacteria is severely impacting our ability to
effectively treat common infections. For Gram-negative bacteria, their intrinsic and acquired …

The cell envelope is essential for survival and adaptation of bacteria. Bacterial membrane
proteins include the major porins that mediate the influx of nutrients and several classes of …

Small-molecule-mediated disruption of bacterial membranes is an important component of
the innate immune response in numerous organisms including humans. Although still under …

There has been an enormous increase in our knowledge of the fundamental steps in the
biosynthesis and assembly of the outer membrane of Gram-negative bacteria …

Gram-negative bacteria are intrinsically resistant to many antibiotics. Species that have
acquired multidrug resistance and cause infections that are effectively untreatable present a …