Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

Acid-Base Homeostasis in End-Stage Renal Disease Page 1 Acid-Base Homeostasis in
End-Stage Renal Disease F. John Gennari Department of Medicine, University of Vermont …

Background: Disorders of acid-base involve the complex interplay of many organ systems
including brain, lungs, kidney, and liver. Compensations for acid-base disturbances within …

The H+ concentration in human blood is kept within very narrow limits,~ 40 nM, despite the
fact that dietary metabolism generates acid and base loads that are added to the systemic …

Potassium homeostasis in man is normally accomplished by appropriate changes in the
renal excretion of this cation in response to random variations in intake. Although this …

Metabolic acidosis is a common complication associated with progressive loss of kidney
function. The diminishing ability of the kidneys to maintain acid–base homeostasis results in …

Kidneys play a pivotal role in the maintenance and regulation of acid-base and electrolyte
homeostasis, which is the prerequisite for numerous metabolic processes and organ …

Acid-base balance is critical for normal life. Acute and chronic disturbances impact cellular
energy metabolism, endocrine signaling, ion channel activity, neuronal activity, and …

It is well established that diet and certain food components have a clear impact on acid‐
base balance. For adults, the following factors are involved: 1) the chemical composition of …

Metabolic acidosis is a common complication of chronic kidney disease. Accumulating
evidence identifies acidosis not only as a consequence of, but as a contributor to, kidney …