Acute GVHD is a strong predictor of full donor CD3+ T cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation

J El‐Cheikh, A Vazquez, R Crocchiolo… - American journal of …, 2012 - Wiley Online Library
The monitoring of chimerism is a standard procedure to assess engraftment and
achievement of full donor lymphoid cells after reduced intensity conditioning (RIC) stem cell …

[HTML][HTML] Predictive factors and impact of full donor T-cell chimerism after reduced intensity conditioning allogeneic stem cell transplantation

M Mohty, O Avinens, C Faucher, P Viens… - …, 2007 - haematologica.org
This study investigated the kinetics of CD3+-T cell chimerism (TCC) in 102 patients receiving
reduced intensity conditioning allogeneic stem cell transplantation (RIC-allo-SCT) from an …

[HTML][HTML] Donor chimerism early after reduced-intensity conditioning hematopoietic stem cell transplantation predicts relapse and survival

J Koreth, HT Kim, S Nikiforow, EL Milford… - Biology of Blood and …, 2014 - Elsevier
The impact of early donor cell chimerism on outcomes of T cell–replete reduced-intensity
conditioning (RIC) hematopoietic stem cell transplantation (HSCT) is ill defined. We …

[HTML][HTML] Does early chimerism testing predict outcomes after allogeneic hematopoietic stem cell transplantation?

L Mountjoy, J Palmer, KL Kunze, N Khera… - Leukemia & …, 2021 - Taylor & Francis
Allogenic stem cell transplantation (HCT) is a potentially curative treatment for patients with
various hematologic malignancies. Following HCT it is common practice to assess …

Full donor chimerism without graft-versus-host disease: the key factor for maximum benefit of pre-emptive donor lymphocyte infusions (pDLI)

J Feliu, V Potter, F Grimaldi, J Clay, L Floro… - Bone Marrow …, 2020 - nature.com
Compared to standard-conditioned regimens, reduced-intensity conditioning and T-cell
depletion deliver lower transplant-related mortality and decreased graft-vs-host disease after …

Correlation between the kinetics of CD3+ chimerism and the incidence of graft-versus-host disease in patients undergoing allogeneic hematopoietic stem cell …

J Rupa-Matysek, K Lewandowski, W Nowak… - Transplantation …, 2011 - Elsevier
Introduction Graft-versus-host disease (GvHD) remains a significant complication after
allogeneic hematopoietic stem cell transplantation (HSCT). Early diagnosis and treatment …

Comparison of donor chimerism following myeloablative and nonmyeloablative allogeneic hematopoietic SCT

DM Mickelson, L Sproat, R Dean, R Sobecks… - Bone marrow …, 2011 - nature.com
Surveillance of hematopoietic chimerism following hematopoietic SCT (HSCT) with
nonmyeloablative (NMA) preparative regimens is standard to assess the need for clinical …

[HTML][HTML] Competitive repopulation and allo-immunologic pressure determine chimerism kinetics after T cell-depleted allogeneic stem cell transplantation and donor …

EAS Koster, PA von dem Borne, P van Balen… - … and Cellular Therapy, 2023 - Elsevier
Extended abstract Background After allogeneic stem cell transplantation (alloSCT), patient-
derived stem cells that survived the pre-transplant conditioning compete with engrafting …

Incomplete chimerism following myeloablative and anti-thymocyte globulin-conditioned hematopoietic cell transplantation is a risk factor for relapse and chronic graft …

RA Khanolkar, G Tripathi, P Dharmani-Khan, R Dabas… - Cytotherapy, 2022 - Elsevier
Background aims The value of routine chimerism determination after myeloablative
hematopoietic cell transplantation (HCT) is unclear, particularly in the setting of anti …

[HTML][HTML] The impact of chimerism patterns and predonor leukocyte infusion lymphopenia on survival following T cell-depleted reduced intensity conditioned transplants

BE Shaw, JL Byrne, E Das-Gupta, GI Carter… - Biology of Blood and …, 2007 - Elsevier
Donor leukocyte infusions (DLI) are frequently required following reduced intensity
conditioned (RIC) allografts to convert mixed chimerism (MC) to full donor chimerism (FDC) …