Circulating microvesicles and exosomes in small cell lung cancer by quantitative proteomics

S Pedersen, KP Jensen, B Honoré, SR Kristensen… - Clinical proteomics, 2022 - Springer
Background Early detection of small cell lung cancer (SCLC) crucially demands highly
reliable markers. Growing evidence suggests that extracellular vesicles carry tumor cell …

Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions

JO Park, DY Choi, DS Choi, HJ Kim, JW Kang… - …, 2013 - Wiley Online Library
Microvesicles (MV s, also known as exosomes, ectosomes, microparticles) are released by
various cancer cells, including lung, colorectal, and prostate carcinoma cells. MV s released …

Comparative proteomic analysis of exosomes and microvesicles in human saliva for lung cancer

Y Sun, C Huo, Z Qiao, Z Shang… - Journal of proteome …, 2018 - ACS Publications
Extracellular vesicles (EVs) are cell-derived microparticles present in most body fluids,
mainly including microvesicles and exosomes. EV-harbored proteins have emerged as …

Triple SILAC quantitative proteomic analysis reveals differential abundance of cell signaling proteins between normal and lung cancer-derived exosomes

DJ Clark, WE Fondrie, A Yang, L Mao - Journal of proteomics, 2016 - Elsevier
Exosomes are 30–100 nm sized membrane vesicles released by cells into the extracellular
space that mediate intercellular communication via transfer of proteins and other biological …

Identification of exosomal microRNA panel as diagnostic and prognostic biomarker for small cell lung cancer

DH Kim, H Park, YJ Choi, K Im, CW Lee, DS Kim… - Biomarker …, 2023 - Springer
Background Small cell lung cancer (SCLC) has an exceptionally poor prognosis; as most of
the cases are initially diagnosed as extensive disease with hematogenous metastasis …

Two microRNAs of plasma-derived small extracellular vesicles as biomarkers for metastatic non-small cell lung cancer

N Geng, Y Qi, W Qin, S Li, H Jin, Y Jiang… - BMC Pulmonary …, 2023 - Springer
Background MicroRNAs (miRNAs) of plasma-derived small extracellular vesicles (sEVs)
have been proven to be associated with metastasis in several types of cancer. This study …

Potential avenues for exosomal isolation and detection methods to enhance small-cell lung cancer analysis

WA Afridi, S Strachan, S Kasetsirikul… - ACS measurement …, 2023 - ACS Publications
Around the world, lung cancer has long been the main factor in cancer-related deaths, with
small-cell lung cancer (SCLC) being the deadliest form of lung cancer. Cancer cell-derived …

Secretome of activated fibroblasts induced by exosomes for the discovery of biomarkers in non‐small cell lung cancer

J Zhang, B Fu, M Li, S Mi - Small, 2021 - Wiley Online Library
Molecules involved in crosstalk between tumor cells and fibroblasts play vital roles in tumor
progression. Extracellular matrix proteins, whose abundance is altered after being affected …

Discovery of a diagnostic biomarker for colon cancer through proteomic profiling of small extracellular vesicles

CH Lee, EJ Im, PG Moon, MC Baek - BMC cancer, 2018 - Springer
Background Small extracellular vesicles (small-EVs) are membranous vesicles that contain
unique information regarding the condition of cells and contribute to the recruitment and …

Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer

B Luo, Z Que, X Lu, D Qi, Z Qiao, Y Yang… - Biological Procedures …, 2023 - Springer
Background Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-related
deaths worldwide, primarily due to its propensity for metastasis. Patients diagnosed with …