A rapid HPLC method for the simultaneous determination of amiodarone and its major metabolite in rat plasma and tissues: a useful tool for pharmacokinetic studies
M Rodrigues, G Alves, A Ferreira… - Journal of …, 2013 - academic.oup.com
A rapid and sensitive high-performance liquid chromatography (HPLC) method was
developed and validated in rat plasma and tissue (heart, liver, kidney and lung) …
developed and validated in rat plasma and tissue (heart, liver, kidney and lung) …
A liquid chromatography–mass spectrometry assay method for simultaneous determination of amiodarone and desethylamiodarone in rat specimens
A Shayeganpour, V Somayaji… - Biomedical …, 2007 - Wiley Online Library
A liquid chromatographic‐mass spectrometry (LC/MS) assay method was developed for the
determination of amiodarone and desethylamiodarone in rat specimens. Analytes were …
determination of amiodarone and desethylamiodarone in rat specimens. Analytes were …
Simultaneous determination of amiodarone and its major metabolite desethylamiodarone in plasma, urine and tissues by high-performance liquid chromatography
TA Plomp, M Engels, EOR De Medina… - … of Chromatography B …, 1983 - Elsevier
A simple and sensitive high-performance liquid chromatographic method for the
simultaneous assay of amiodarone and desethylarniodarone in plasma, urine and tissues …
simultaneous assay of amiodarone and desethylarniodarone in plasma, urine and tissues …
Determination of amiodarone and desethylamiodarone in horse plasma and urine by high-performance liquid chromatography combined with UV detection and …
A Maes, K Baert, S Croubels, D De Clercq… - … of Chromatography B, 2006 - Elsevier
A rapid method for the quantification of amiodarone and desethylamiodarone in animal
plasma using high-performance liquid chromatography combined with UV detection (HPLC …
plasma using high-performance liquid chromatography combined with UV detection (HPLC …
Simultaneous measurement of amiodarone and desethylamiodarone in human plasma and serum by stable isotope dilution liquid chromatography–tandem mass …
J Kuhn, C Götting, K Kleesiek - Journal of pharmaceutical and biomedical …, 2010 - Elsevier
A stable isotope dilution liquid chromatography–electrospray ionization tandem mass
spectrometry (LC–MS/MS) assay to measure amiodarone, the most frequently used agent …
spectrometry (LC–MS/MS) assay to measure amiodarone, the most frequently used agent …
Determination of amiodarone and desethylamiodarone in human plasma by high-performance liquid chromatography–electrospray ionization tandem mass …
M Kollroser, C Schober - Journal of Chromatography B, 2002 - Elsevier
A sensitive and specific high-performance liquid chromatography–electrospray ionization-
tandem mass spectrometry (HPLC–ESI-MS–MS) method has been developed for the …
tandem mass spectrometry (HPLC–ESI-MS–MS) method has been developed for the …
[PDF][PDF] High-performance liquid chromatographic assay of amiodarone in rat plasma
AS Jun, DR Brocks - J Pharm Pharmaceut Sci, 2001 - sites.ualberta.ca
Purpose. A high-performance liquid chromatographic method is described for the
determination of amiodarone in rat plasma. Methods. After liquid-liquid extraction, the …
determination of amiodarone in rat plasma. Methods. After liquid-liquid extraction, the …
Simultaneous determination of amiodarone and its metabolite desethylamiodarone by high-performance liquid chromatography with chemiluminescent detection
T Pérez-Ruiz, C Martínez-Lozano… - Analytica chimica …, 2008 - Elsevier
A novel method was developed for the determination of amiodarone and
desethylamiodarone by high-performance liquid chromatography (HPLC) coupled with …
desethylamiodarone by high-performance liquid chromatography (HPLC) coupled with …
[引用][C] High-performance liquid chromatographic analysis of amiodarone and desethylamiodarone in serum
M Bliss, M Mayersohn, P Nolan - Journal of Chromatography B: Biomedical …, 1986 - Elsevier
Amiodarone, an antiarrhythmic benzofuran derivative has been widely used outside of the
United States for as long as ten years [I]. In the USA it remains an investigational drug which …
United States for as long as ten years [I]. In the USA it remains an investigational drug which …
Identification and quantitation of novel metabolites of amiodarone in plasma of treated patients
HR Ha, L Bigler, B Wendt, M Maggiorini… - European journal of …, 2005 - Elsevier
In mammals, mono-N-desethylamiodarone (MDEA) is the only known metabolite of
amiodarone. Our previous experiments demonstrated that in vitro MDEA may be …
amiodarone. Our previous experiments demonstrated that in vitro MDEA may be …
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