[HTML][HTML] Global hemostatic profiling in patients with decompensated cirrhosis and bacterial infections

A Zanetto, E Campello, C Bulato, S Gavasso… - JHEP Reports, 2022 - Elsevier
Background & Aims Bacterial infections in cirrhosis are associated with increased bleeding
risk. To assess the factors responsible for bleeding tendency in patients with bacterial …

[PDF][PDF] Coagulation parameters and major bleeding in critically ill patients with cirrhosis

A Drolz, T Horvatits, K Roedl, K Rutter, K Staufer… - …, 2016 - Wiley Online Library
Disturbances of coagulation and hemostasis are common in patients with liver cirrhosis. The
typical laboratory pattern mimics disseminated intravascular coagulation (DIC). The aim of …

[HTML][HTML] Haemostasis in cirrhosis: understanding destabilising factors during acute decompensation

A Zanetto, P Northup, L Roberts, M Senzolo - Journal of Hepatology, 2023 - Elsevier
Hospitalised patients with decompensated cirrhosis are in a rebalanced haemostatic state
due to a parallel decline in both pro-and anti-haemostatic pathways. However, this …

[PDF][PDF] Infection and hemostasis in decompensated cirrhosis: a prospective study using thrombelastography

GV Papatheodoridis, D Patch, GJ Webster… - …, 1999 - Wiley Online Library
Bacterial infections are common complications in decompensated cirrhosis, but their
relationship with hemostasis has not been studied. We prospectively assessed whether …

[HTML][HTML] Global hemostatic status in patients with acute‐on‐chronic liver failure and septics without underlying liver disease

T Lisman, B Arefaine, J Adelmeijer, A Zamalloa… - Journal of Thrombosis …, 2021 - Elsevier
Essentials• Liver diseases are associated with profound hemostatic changes proportional to
severity of illness.• Hemostatic changes in acute‐on‐chronic liver failure (ACLF) may in part …

The evolving knowledge on primary hemostasis in patients with cirrhosis: a comprehensive review

A Zanetto, E Campello, M Senzolo, P Simioni - Hepatology, 2024 - journals.lww.com
Patients with cirrhosis develop complex alterations in primary hemostasis that include both
hypocoagulable and hypercoagulable features. This includes thrombocytopenia, multiple …

Balanced haemostasis with both hypo-and hyper-coagulable features in critically ill patients with acute-on-chronic-liver failure

C Fisher, VC Patel, SH Stoy, A Singanayagam… - Journal of Critical …, 2018 - Elsevier
Background Cirrhotic patients have complex haemostatic abnormalities. Current evidence
suggests stable cirrhotic (SC) patients have a “re-balanced” haemostatic state. However …

Hemostatic balance in patients with liver cirrhosis: report of a consensus conference

A Andriulli, A Tripodi, P Angeli, M Senzolo… - Digestive and Liver …, 2016 - Elsevier
Patients with cirrhosis present with hemostatic alterations secondary to reduced availability
of pro-coagulant and anti-coagulant factors. The net effect of these changes is a rebalanced …

Prognostic significance of bacterial infection in bleeding cirrhotic patients: a prospective study

B Bernard, JF Cadranel, D Valla, S Escolano, V Jarlier… - Gastroenterology, 1995 - Elsevier
Background/Aims: In cirrhotic patients, bacterial infection is frequently associated with
gastrointestinal bleeding and seems to increase mortality. The aims of this study were to …

[HTML][HTML] Haemostatic alterations and management of haemostasis in patients with cirrhosis

T Lisman, SH Caldwell, NM Intagliata - Journal of Hepatology, 2022 - Elsevier
Patients with cirrhosis frequently acquire complex changes in their haemostatic system
including a decreased platelet count and decreased levels of various haemostatic proteins …