[HTML][HTML] International normalized ratio (INR)

S Shikdar, R Vashisht, PT Bhattacharya - 2018 - europepmc.org
International normalized ratio (INR) is the preferred test of choice for patients taking vitamin
K antagonists (VKA). It can also be used to assess the risk of bleeding or the coagulation …

Thromboplastin standards

A Van den Besselaar, V Chantarangkul, A Tripodi - Biologicals, 2010 - Elsevier
The Prothrombin Time (PT) test is used for monitoring of treatment with Vitamin K-
antagonists (VKA). The result of the PT test should be expressed as the International …

How to generate a more accurate laboratory-based international normalized ratio: solutions to obtaining or verifying the mean normal prothrombin time and …

EJ Favaloro - Seminars in Thrombosis and Hemostasis, 2019 - thieme-connect.com
Although the landscape of anticoagulation therapy is evolving, vitamin K antagonists (VKAs)
such as warfarin remain an anticoagulant of choice for many clinicians and their patients …

A critical evaluation of the prothrombin time for monitoring oral anticoagulant therapy

CM Jackson, MP Esnouf, TL Lindahl - Pathophysiology of haemostasis …, 2003 - karger.com
The Quick prothrombin time is the most common clotting test performed, principally for
monitoring oral anticoagulant therapy. The International Normalized Ratio (INR) for …

Standardization of the INR: how good is your laboratory's INR and can it be improved?

EJ Favaloro, DM Adcock - Seminars in thrombosis and …, 2008 - thieme-connect.com
The prothrombin time (PT) assay is the most clinically ordered coagulation test and is most
often used for monitoring of vitamin K antagonist (VKA) therapy (eg, warfarin), where results …

International normalized ratio monitoring of vitamin K antagonist therapy: comparative performance of point-of-care and laboratory-derived testing

R Bonar, S Mohammed… - Seminars in thrombosis …, 2015 - thieme-connect.com
The monitoring of warfarin therapy using the international normalized ratio (INR) has now
moved outside the laboratory's control by use of point-of-care (POC) devices. Although this …

Improving the harmonisation of the International Normalized Ratio (INR): time to think outside the box?

EJ Favaloro, W McVicker, S Hamdam… - Clinical chemistry and …, 2010 - degruyter.com
The prothrombin time (PT) assay is the most often requested coagulation test and used
primarily for monitoring Vitamin K antagonist therapy, where results may be expressed as an …

Variability of INR in patients on stable long-term treatment with phenprocoumon and acenocoumarol and implications for analytical quality requirements

JHH van Geest-Daalderop… - Thrombosis and …, 2009 - thieme-connect.com
Within each patient treated with vitamin K antagonist (VKA), variation of the international
normalised ratio (INR) occurs over the treatment period. The purpose of the present study …

[HTML][HTML] Vitamin K antagonist use: evidence of the difficulty of achieving and maintaining target INR range and subsequent consequences

JR Schein, CM White, WW Nelson, J Kluger… - Thrombosis journal, 2016 - Springer
Vitamin K antagonists (VKAs) are effective oral anticoagulants that are titrated to a narrow
therapeutic international normalized ratio (INR) range. We reviewed published literature …

[HTML][HTML] Prediction of bleeding risk in patients taking vitamin K antagonists using thrombin generation testing

S Bloemen, S Zwaveling, H Ten Cate… - PLoS …, 2017 - journals.plos.org
Until recently, vitamin K antagonists (VKAs) were the mainstay of oral anticoagulant
treatment with bleeding as the most prevalent adverse effect. One to four percent of patients …