A transposable element, or transposon, is a discrete segment of DNA that can move
between non-homologous DNA sites in a host cell. The movement of a transposable …

To spread, transposons must integrate into target sites without disruption of essential genes
while avoiding host defense systems. Tn7-like transposons employ multiple mechanisms for …

Transposons play an integral role in bacterial adaptation, therefore it is important to
understand the chemical steps and regulatory factors that govern their mobility. The …

Tn7 transposable elements are unique for their highly specific, and sometimes
programmable, target-site selection mechanisms and precise insertions. All the elements in …

Transposons are mobile genetic elements that can move between locations in DNA that lack
homology. Transposons play an important role in the evolution of genomes in every domain …

Most transposons display target site selectivity, inserting preferentially into sites that contain
particular features. The bacterial transposon Tn7 possesses the unusual ability to recognize …

Tn10, like several other transposons, exhibits a marked preference for integration into
particular target sequences. Such sequences are referred to as integration hotspots and …

The bacterial transposon Tn10 inserts preferentially into specific DNA sequences. DNA
footprinting and interference studies have revealed that the Tn10-encoded transposase …

The Tn7 transposon avoids inserting into a target DNA that contains a pre-existing copy of
Tn7. This phenomenon, known as 'target immunity', is established when TnsB, a Tn7 …

Abstract The Tn3-deletion method [Davies and Hutchison, Nucleic Acids Res. 19, 5731–
5738,(1991)] was used to sequence a 9.4 kb DNA fragment. Transpositional 'warm'spots …