Infectious agents can trigger autoimmune responses in a number of chronic inflammatory
diseases. Lyme arthritis, which is caused by the tick-transmitted spirochaete Borrelia …

Lyme arthritis differs in many respects from other bacterial causes of arthritis. Based on an
observation made for a patient with Lyme arthritis, we propose that the pathogenesis of joint …

Before the first description of Lyme arthritis in 1976, patients with this disease were often
thought to have juvenile or adult rheumatoid arthritis. It is now known that Lyme arthritis is …

Abstract Background. Control of Lyme disease is attributed predominantly to innate and
adaptive T-helper 1 cell (TH1) immune responses, whereas the role of T-helper 17 cell …

▪ Abstract Lyme disease, caused by Borrelia burgdorferi, causes a multisystem inflammatory
ailment, although the precise means of tissue damage are not well understood. It is clear …

Lyme borreliosis in humans is an inflammatory disease affecting multiple organ systems,
including the nervous system, cardiovascular system, joints and muscles. The causative …

Arthritis is one of the most prominent features of Lyme disease, the tick-borne illness caused
by Borrelia burgdorferi. Although the pathogenesis of Lyme arthritis is complex and still …

Lyme disease Borrelia are obligately parasitic, tick-transmitted, invasive, persistent bacterial
pathogens that cause disease in humans and non-reservoir vertebrates primarily through …

Lyme disease, caused by spirochetes of the Borrelia burgdorferi sensu lato complex
(hereinafter referred to as Lyme borrelia), is the most common tick-borne infection in the …

Lyme disease, infection with the tick-borne spirochete Borrelia burgdorferi, causes both
specific and nonspecific symptoms. In untreated chronic infection, specific manifestations …