The development of metastasis is the major cause of death in cancer patients. In certain
instances, this occurs shortly after primary tumor detection and treatment, indicating these …

Background The ability of a tumor to become dormant in response to suboptimal conditions
has recently been recognized as a key step in tumor progression. Tumor dormancy has …

Metastasis and relapse accounts for the great majority of cancer-related deaths. Most
metastatic lesions are micro metastases that have the capacity to remain in a non-dividing …

Metastasis, a multistep process during which tumor cells disseminate to secondary organs,
represents the main cause of death for cancer patients. Metastatic dormancy is a late stage …

The majority of cancer deaths are due to metastases that can occur years or decades after
primary tumor diagnosis and treatment. Disseminated tumor cells (DTCs) surviving in a …

In this thematic issue, several mechanisms of tumor dormancy and relapse are discussed.
The reviews suggest mutual interactions and communications between malignant cells and …

Tumor dormancy, a clinically undetectable state of cancer, makes a major contribution to the
development of multidrug resistance (MDR), minimum residual disease (MRD), tumor …

Cancer dormancy is a stage in tumor progression in which residual disease remains occult
and asymptomatic for a prolonged period of time. Dormant tumor cells can be present as …

Metastasis is the main cause of cancer-related deaths. Disseminated tumor cells (DTCs),
which seed metastasis, can remain undetected in a dormant state for decades after …

Cancer is a leading cause of disease-related mortality worldwide. Drug resistance is one of
the primary reasons for the failure of anticancer therapy. There are a number of underlying …