The primary aim of the present study was to examine the effect of maternal age (in months)
on mitochondrial DNA copy number (Mt number), ATP content and IVF outcome of bovine …

Age-associated deterioration in both the quality and quantity of mitochondria occurs in older
women. The main aim of this study was to examine the effect of age on mitochondrial DNA …

Mitochondria have a broad range of functions that affect reproduction, and structural as well
as quantitative variation in mtDNA has been associated with gamete quality and …

Mitochondria are responsible for the production of ATP, which drives cellular metabolic and
biosynthetic processes. This is the first study to quantify the mtDNA copy number across all …

Purpose To investigate the correlation between the ooplasmic volume and the number of
mitochondrial DNA (mtDNA) copies in embryos and how they may affect fecundity. Method …

The development of mammalian oocytes is dependent on bidirectional signaling with the
surrounding cumulus cells. Among the numerous factors that contribute to oocyte …

The extensive replication of mitochondria during oogenesis and the wide variability in
mitochondrial DNA (mtDNA) copy numbers present in fully grown oocytes indicate that …

OBJECTIVE: To determine the content of mitochondrial DNA (mtDNA) in oocytes from a
range of patients with fertilization success and failure. DESIGN: Analysis of mtDNA content …

ATP is critical for oocyte maturation, fertilization, and subsequent embryo development. Both
mitochondrial membrane potential and copy number expand during oocyte maturation. In …

The mitochondrion is explicitly involved in cytoplasmic regulation and is the cell's major
generator of ATP. Our aim was to determine whether mitochondria alone could influence …