[HTML][HTML] Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet-a neglected source for uEVs

L Musante, SV Bontha, S La Salvia… - Scientific Reports, 2020 - nature.com
Urinary extracellular vesicles (uEVs) provide bio-markers for kidney and urogenital
diseases. Centrifugation is the most common method used to enrich uEVs. However, a …

Urinary extracellular vesicles: Assessment of pre‐analytical variables and development of a quality control with focus on transcriptomic biomarker research

K Barreiro, OP Dwivedi, S Valkonen… - Journal of …, 2021 - Wiley Online Library
Urinary extracellular vesicles (uEV) are a topical source of non‐invasive biomarkers for
health and diseases of the urogenital system. However, several challenges have become …

Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles

U Erdbrügger, CJ Blijdorp, IV Bijnsdorp… - Journal of …, 2021 - Wiley Online Library
Urine is commonly used for clinical diagnosis and biomedical research. The discovery of
extracellular vesicles (EV) in urine opened a new fast‐growing scientific field. In the last …

Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment

L Musante, D Tataruch-Weinert… - Journal of …, 2017 - Taylor & Francis
Urinary extracellular vesicles (UEVs) appear an ideal source of biomarkers for kidney and
urogenital diseases. The majority of protocols designed for their isolation are based on …

Urinary extracellular vesicles: Origin, role as intercellular messengers and biomarkers; efficient sorting and potential treatment options

P Svenningsen, R Sabaratnam, BL Jensen - Acta Physiologica, 2020 - Wiley Online Library
Urinary extracellular vesicles (uEVs) are a heterogenous group of vesicles consisting mainly
of microvesicles and exosomes that originate predominantly (99.96%) from kidney, the …

Urinary extracellular vesicles and the kidney: biomarkers and beyond

M Salih, R Zietse, EJ Hoorn - American Journal of …, 2014 - journals.physiology.org
Extracellular vesicles have been isolated in various body fluids, including urine. The cargo
of urinary extracellular vesicles (uEVs) is composed of proteins and nucleic acids reflecting …

[HTML][HTML] The quick reference card “Storage of urinary EVs”–A practical guideline tool for research and clinical laboratories

ME van Royen, C Soekmadji, C Grange… - Journal of …, 2023 - ncbi.nlm.nih.gov
Dear Editor, The high diagnostic potential of urinary extracellular vesicles (uEVs) for
urogenital disease has been recognized for more than a decade. This is emphasized by the …

Comparing approaches to normalize, quantify, and characterize urinary extracellular vesicles

CJ Blijdorp, OAZ Tutakhel, TA Hartjes… - Journal of the …, 2021 - journals.lww.com
Background Urinary extracellular vesicles (uEVs) are a promising source for biomarker
discovery, but optimal approaches for normalization, quantification, and characterization in …

Isolation and characterization of human urine extracellular vesicles

Z Liu, DM Cauvi, EMA Bernardino, B Lara… - Cell Stress and …, 2018 - Springer
Extracellular vesicles (ECV) reflect physiological or pathological conditions, emerging as
potential biomarkers for disease. They can be obtained from a variety of body fluids …

[HTML][HTML] Single extracellular vesicle analysis performed by imaging flow cytometry and nanoparticle tracking analysis evaluate the accuracy of urinary extracellular …

M Droste, T Tertel, S Jeruschke, R Dittrich… - International journal of …, 2021 - mdpi.com
Small extracellular vesicles isolated from urine (uEVs) are increasingly recognized as
potential biomarkers. Meanwhile, different uEV preparation strategies exist. Conventionally …