Emphysema Index Based on Hyperpolarized 3He or 129Xe Diffusion MRI: Performance and Comparison with Quantitative CT and Pulmonary …

S Tafti, WJ Garrison, JP Mugler III, YM Shim, TA Altes… - Radiology, 2020 - pubs.rsna.org
Background Apparent diffusion coefficient (ADC) maps of inhaled hyperpolarized gases
have shown promise in the characterization of emphysema in patients with chronic …

Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes—initial experience

M Salerno, EE de Lange, TA Altes, JD Truwit… - Radiology, 2002 - pubs.rsna.org
PURPOSE: To quantitatively evaluate hyperpolarized helium 3 (3He) diffusion magnetic
resonance (MR) images of the lung in patients with emphysema and to determine whether …

Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

S Diaz, I Casselbrant, E Piitulainen… - European journal of …, 2009 - Elsevier
PURPOSE: To compare apparent diffusion coefficient (ADC) measurements from
hyperpolarized (HP) helium (3He)-magnetic resonance imaging (MRI) with quantitative data …

Hyperpolarized 3He apparent diffusion coefficient MRI of the lung: Reproducibility and volume dependency in healthy volunteers and patients with emphysema

S Diaz, I Casselbrant, E Piitulainen… - Journal of Magnetic …, 2008 - Wiley Online Library
Purpose To measure the apparent diffusion coefficient (ADC) of hyperpolarized (HP) 3He
gas using diffusion weighted MRI in healthy volunteers and patients with emphysema and …

Evaluation of emphysema severity and progression in a rabbit model: comparison of hyperpolarized 3He and 129Xe diffusion MRI with lung morphometry

JF Mata, TA Altes, J Cai, K Ruppert… - Journal of applied …, 2007 - journals.physiology.org
The apparent diffusion coefficients (ADCs) of hyperpolarized 3He and 129Xe gases were
measured in the lungs of rabbits with elastase-induced emphysema and correlated against …

Progression of Emphysema in a 12-month Hyperpolarized 3He-MRI Study: Lacunarity Analysis Provided a More Sensitive Measure than Standard ADC Analysis1

S Diaz, I Casselbrant, E Piitulainen, P Magnusson… - Academic radiology, 2009 - Elsevier
RATIONALE AND OBJECTIVES: Inhaled hyperpolarized 3He magnetic resonance (MR)
imaging has been used to measure alveolar size in patients with emphysema. The aim of …

Hyperpolarized 3He ventilation defects and apparent diffusion coefficients in chronic obstructive pulmonary disease: preliminary results at 3.0 Tesla

G Parraga, A Ouriadov, A Evans, S McKay… - Investigative …, 2007 - journals.lww.com
Objective: Hyperpolarized 3 He magnetic resonance imaging (3 He MRI) at 3.0 Tesla of
healthy volunteers and chronic obstructive pulmonary disease (COPD) patients was …

Chronic Obstructive Pulmonary Disease: Lobar Analysis with Hyperpolarized 129Xe MR Imaging

TN Matin, N Rahman, AH Nickol, M Chen, X Xu… - Radiology, 2017 - pubs.rsna.org
Purpose To compare lobar ventilation and apparent diffusion coefficient (ADC) values
obtained with hyperpolarized xenon 129 (129Xe) magnetic resonance (MR) imaging to …

Quantitative 1H and hyperpolarized 3He magnetic resonance imaging: Comparison in chronic obstructive pulmonary disease and healthy never-smokers

AM Owrangi, JX Wang, A Wheatley… - European Journal of …, 2014 - Elsevier
Objective The aim of this study was to quantitatively evaluate the relationship between short
echo time pulmonary 1 H magnetic resonance imaging (MRI) signal intensity (SI) and 3 He …

Effects of diffusion time on short‐range hyperpolarized 3He diffusivity measurements in emphysema

DS Gierada, JC Woods, AJ Bierhals… - Journal of Magnetic …, 2009 - Wiley Online Library
Purpose To characterize the effect of diffusion time on short‐range hyperpolarized 3He
magnetic resonance imaging (MRI) diffusion measurements across a wide range of …