[PDF][PDF] Enabling Pulmonary Drug Delivery with Nanoporous Particles

IZP Nabavi, A Feiler - ddl-conference.com
A novel pulmonary drug delivery system has been developed comprising of nanoporous,
micron-sized, amorphous silica particles to encapsulate drug substances. The particle size …

[HTML][HTML] Influence of particle diameter on aerosolization performance and release of budesonide loaded mesoporous silica particles

I van der Zwaan, GA Pilkington, G Frenning… - European Journal of …, 2024 - Elsevier
The potential of micron-sized amorphous mesoporous silica particles as a novel controlled
release drug delivery system for pulmonary administration has been investigated …

Excipient-free nanoporous microparticles of budesonide for pulmonary delivery

LM Nolan, L Tajber, BF McDonald, AS Barham… - European Journal of …, 2009 - Elsevier
The aim of this study was to investigate the application of a spray-drying process for the
production of nanoporous microparticles (NPMPs) to budesonide, and to characterise the …

Porous particle technology: novel approaches to deep lung delivery

S Sawatdee, N Changsan, T Srichana… - Pulmonary Drug Delivery …, 2023 - Springer
Porous particle technologies are widely used to deliver small and large molecular drugs to
the lung for local and systemic treatment. Porous particles are able to deliver high drug …

Mesoporous silica particles for pulmonary drug delivery: Multiple routes towards controlled release

I van der Zwaan, GA Pilkington, G Frenning… - 2023 - diva-portal.org
Mesoporous silica particles for pulmonary drug delivery: Multiple routes towards controlled
release diva-portal.org Digitala Vetenskapliga Arkivet Simple search Advanced search …

Modern trends in the formulation of microparticles for lung delivery using porogens: methods, principles and examples

A Peštálová, J Gajdziok - Pharmaceutical Development and …, 2024 - Taylor & Francis
Inhalation drug administration is increasingly used for local pharmacotherapy of lung
disorders and as an alternative route for systemic drug delivery. Modern inhalation powder …

Aerosol droplet delivery of mesoporous silica nanoparticles: A strategy for respiratory-based therapeutics

X Li, M Xue, OG Raabe, HL Aaron, EA Eisen… - … , Biology and Medicine, 2015 - Elsevier
A highly versatile nanoplatform that couples mesoporous silica nanoparticles (MSNs) with
an aerosol technology to achieve direct nanoscale delivery to the respiratory tract is …

[HTML][HTML] Inhalable porous particles as dual micro-nano carriers demonstrating efficient lung drug delivery for treatment of tuberculosis

JEC Pacheco, T Yalovenko, A Riaz, N Kotov… - Journal of Controlled …, 2024 - Elsevier
Inhalation therapy treating severe infectious disease is among the more complex and
emerging topics in controlled drug release. Micron-sized carriers are needed to deposit …

Recent advances in controlled pulmonary drug delivery

Z Liang, R Ni, J Zhou, S Mao - Drug Discovery Today, 2015 - Elsevier
Highlights•Controlled pulmonary drug delivery is a promising system.•Novel strategies are
developed to avoid the formidable airway clearance mechanisms.•Large porous particles …

Factors affecting the deposition of inhaled porous drug particles

CJ Musante, JD Schroeter, JA Rosati… - Journal of …, 2002 - Elsevier
Recent findings indicate that the inhalation of large manufactured porous particles may be
particularly effective for drug delivery. In this study, a mathematical model was employed to …