Rheumatoid arthritis (RA) is characterized by immune dysfunctions and chronic
inflammation that mainly affects diarthrodial joints. Genetics has long been surveyed in …

Rheumatoid arthritis is an immune-mediated disease that primarily affects diarthrodial joints.
Susceptibility and severity of this disease are influenced by nongenetic factors, such as …

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is
characterized by synovial hyperplasia and progressive joint destruction. The activation of RA …

Rheumatoid arthritis is an autoimmune disease characterized by chronic joint inflammation
and progressive destruction of cartilage and bone which leads to ultimately loss of function …

Fibroblast-like synoviocytes (FLSs) constitute a major cell subset of rheumatoid arthritis (RA)
synovia. Dysregulation of microRNAs (miRNAs) has been implicated in activation and …

MicroRNAs (miRNAs) are endogenous, non-coding, single-stranded RNAs about 21
nucleotides in length. miRNAs have been shown to regulate gene expression and thus …

Rheumatoid arthritis (RA) is a complex chronic systematic disease with progressive
destruction of the joints by invasive synoviocytes. To characterize the key regulators …

The role of genetic and epigenetic factors in the development of rheumatic diseases has
been an interesting field of research over the past decades all around the world. Research …

Within the past years, more and more attention has been devoted to the epigenetic
dysregulation that provides an additional window for understanding the possible …

Rheumatoid arthritis (RA) is a symmetrical polyarticular disease of unknown aetiology that
affects primarily the articular cartilage and bone. Characteristic features of RA pathogenesis …