Colorectal cancer (CRC) is one of the most frequent and deadly forms of cancer. About half
of patients are affected by metastasis, with the cancer spreading to eg, liver, lungs or the …

The immune system is able to recognize and eliminate tumor cells. Some tumors, including
colorectal cancer (CRC), induce immune tolerance via different mechanisms of …

Colorectal cancer (CRC) is a prevalent gastrointestinal cancer posing significant clinical
challenges. CRC management traditionally involves surgery, often coupled with …

Solid tumors are rich ecosystems of numerous different cell types whose interactions lead to
immune escape and resistance to immunotherapy in virtually all patients with metastatic …

There are increasing incidences and mortality rates for colorectal cancer in the world. It is
common for chemotherapy and radiation given to patients with colorectal cancer to cause …

Metastatic colorectal cancer (mCRC) is a leading cause of cancer-related mortality with a 5-
year overall survival rate of 13%. Despite recent advances in cancer immunotherapy, only …

Cancer is an important global issue with increasing incidence and mortality, placing a
substantial burden on the healthcare system. Colorectal cancer is the third most common …

Immunotherapy in the metastatic setting has drastically altered the landscape of treatment
for various types of malignancy, including colorectal cancer. The category of immune …

Important colorectal cancer (CRC) studies in 2021, including a new standard of care for first-
line treatment of MSI-H–dMMR metastatic CRC, single-cell and spatial analysis of primary …

Simple Summary Late-stage colorectal cancer treatment often involves chemotherapy and
radiation that can cause dose-limiting toxicity, and therefore there is great interest in …