Biomarkers in acute kidney injury–pathophysiological basis and clinical performance

EV Schrezenmeier, J Barasch, K Budde… - Acta …, 2017 - Wiley Online Library
Various biomarkers of acute kidney injury (AKI) have been discovered and characterized in
the recent past. These molecules can be detected in urine or blood and signify structural …

A basic science view of acute kidney injury biomarkers

JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …

Biomarkers of kidney injury

A Urbschat, N Obermüller, A Haferkamp - Biomarkers, 2011 - Taylor & Francis
Context: Acute kidney injury (AKI) represents a common serious clinical problem. Up to date
mortality due to AKI, especially in intensive care units, has not been changed significantly …

Current concepts and advances in biomarkers of acute kidney injury

Y Wen, CR Parikh - Critical reviews in clinical laboratory sciences, 2021 - Taylor & Francis
Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

Biomarkers for early detection of acute kidney injury

MS Rizvi, KB Kashani - The Journal of Applied Laboratory …, 2017 - academic.oup.com
Background Acute kidney injury (AKI) is common in hospitalized patients and is associated
with increased morbidity, mortality, and cost. Currently, AKI is diagnosed after symptoms …

Biomarkers of acute kidney injury: the pathway from discovery to clinical adoption

K Kashani, W Cheungpasitporn… - Clinical Chemistry and …, 2017 - degruyter.com
Acute kidney injury (AKI) is a common complication of critical illnesses and has a significant
impact on outcomes, including mortality and morbidities. Unfortunately, apart from …

Advances in the study of subclinical AKI biomarkers

C Zou, C Wang, L Lu - Frontiers in Physiology, 2022 - frontiersin.org
Acute kidney injury (AKI) is a prevalent and serious illness in all clinical departments, with a
high morbidity and death rate, particularly in intensive care units, where prevention and …

Proficient novel biomarkers guide early detection of acute kidney injury: a review

S Jana, P Mitra, S Roy - Diseases, 2022 - mdpi.com
The definition of acute kidney injury (AKI), despite improvements in criteria, continues to be
based on the level of serum creatinine and urinary output that do not specifically indicate …

Role of new biomarkers: functional and structural damage

E Tsigou, V Psallida, C Demponeras… - … care research and …, 2013 - Wiley Online Library
Traditional diagnosis of acute kidney injury (AKI) depends on detection of oliguria and rise of
serum creatinine level, which is an unreliable and delayed marker of kidney damage …

A long journey for acute kidney injury biomarkers

DJ Oh - Renal failure, 2020 - Taylor & Francis
Acute kidney injury (AKI) is a life-threatening illness that continues to have an in-hospital
mortality rate of patients with AKI ranges from 20% to 50% or greater, depending on …