Nuclear compartments: an incomplete primer to nuclear compartments, bodies, and genome organization relative to nuclear architecture
AS Belmont - Cold Spring Harbor perspectives in biology, 2022 - cshperspectives.cshlp.org
This work reviews nuclear compartments, defined broadly to include distinct nuclear
structures, bodies, and chromosome domains. It first summarizes original cytological …
structures, bodies, and chromosome domains. It first summarizes original cytological …
Chromosome territories–a functional nuclear landscape
Understanding nuclear architecture is indispensable for understanding the cell-type-
dependent orchestration of active and silent genes and other nuclear functions, such as …
dependent orchestration of active and silent genes and other nuclear functions, such as …
Genome organization around nuclear speckles
Y Chen, AS Belmont - Current opinion in genetics & development, 2019 - Elsevier
Higher eukaryotic cell nuclei are highly compartmentalized into bodies and structural
assemblies of specialized functions. Nuclear speckles/IGCs are one of the most prominent …
assemblies of specialized functions. Nuclear speckles/IGCs are one of the most prominent …
The contribution of nuclear compartmentalization to gene regulation
M Carmo-Fonseca - Cell, 2002 - cell.com
Recent developments in live-cell imaging are challenging our stereotyped view of the fixed
cell nucleus. The emerging picture is that nuclear processes may rely on a constant flow of …
cell nucleus. The emerging picture is that nuclear processes may rely on a constant flow of …
Whole-genome screening identifies proteins localized to distinct nuclear bodies
The nucleus is a unique organelle that contains essential genetic materials in chromosome
territories. The interchromatin space is composed of nuclear subcompartments, which are …
territories. The interchromatin space is composed of nuclear subcompartments, which are …
Nuclear bodies: multifaceted subdomains of the interchromatin space
AG Matera - Trends in cell biology, 1999 - cell.com
Higher-eukaryotic nuclei contain numerous morphologically distinct substructures that are
collectively called nuclear bodies. Although the precise functions of these subdomains …
collectively called nuclear bodies. Although the precise functions of these subdomains …
Nuclear compartments and gene regulation
M Cockell, SM Gasser - Current opinion in genetics & development, 1999 - Elsevier
Improvements in fluorescence microscopy have allowed us to explore the three-dimensional
organization of the nucleus in ways that were impossible ten years ago, revealing …
organization of the nucleus in ways that were impossible ten years ago, revealing …
The nuclear envelope as a chromatin organizer
N Zuleger, MI Robson, EC Schirmer - Nucleus, 2011 - Taylor & Francis
In the past 15 years our perception of nuclear envelope function has evolved perhaps nearly
as much as the nuclear envelope itself evolved in the last 3 billion years. Historically viewed …
as much as the nuclear envelope itself evolved in the last 3 billion years. Historically viewed …
[HTML][HTML] The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments
Recent methodological advancements in microscopy and DNA sequencing-based methods
provide unprecedented new insights into the spatio-temporal relationships between …
provide unprecedented new insights into the spatio-temporal relationships between …
[HTML][HTML] Genome-wide maps of nuclear lamina interactions in single human cells
Mammalian interphase chromosomes interact with the nuclear lamina (NL) through
hundreds of large lamina-associated domains (LADs). We report a method to map NL …
hundreds of large lamina-associated domains (LADs). We report a method to map NL …