The quantum tunneling of ions model can explain the pathophysiology of tinnitus

BM Al-Rawashdeh, AB Qaswal, A Suleiman, FM Zayed… - Brain Sciences, 2022 - mdpi.com
Tinnitus is a well-known pathological entity in clinical practice. However, the
pathophysiological mechanisms behind tinnitus seem to be elusive and cannot provide a …

Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model

R Schaette, D McAlpine - Journal of Neuroscience, 2011 - Soc Neuroscience
Ever since Pliny the Elder coined the term tinnitus, the perception of sound in the absence of
an external sound source has remained enigmatic. Traditional theories assume that tinnitus …

Quantum mechanical aspects in the pathophysiology of neuropathic pain

S Nawafleh, AB Qaswal, O Alali, FM Zayed… - Brain Sciences, 2022 - mdpi.com
Neuropathic pain is a challenging complaint for patients and clinicians since there are no
effective agents available to get satisfactory outcomes even though the pharmacological …

The potassium channels: Neurobiology and pharmacology of tinnitus

H Lai, M Gao, H Yang - Journal of Neuroscience Research, 2024 - Wiley Online Library
Tinnitus is a widespread public health issue that imposes a significant social burden. The
occurrence and maintenance of tinnitus have been shown to be associated with abnormal …

Mathematical modeling of ion quantum tunneling reveals novel properties of voltage-gated channels and quantum aspects of their pathophysiology in excitability …

AB Qaswal, O Ababneh, L Khreesha, A Al-Ani… - Pathophysiology, 2021 - mdpi.com
Voltage-gated channels are crucial in action potential initiation and propagation and there
are many diseases and disorders related to them. Additionally, the classical mechanics are …

[PDF][PDF] A theoretical study to explain the referred pain phenomenon and its characteristics via quantum tunneling of potassium Ions through the channels of neuronal …

AB Qaswal - NeuroQuantology, 2019 - researchgate.net
When action potentials occur in neurons, sodium ions diffuse to inside neuronal membrane
during depolarization whereas potassium ions diffuse to the outside during repolarization, in …

Computational models of neurophysiological correlates of tinnitus

R Schaette, R Kempter - Frontiers in systems neuroscience, 2012 - frontiersin.org
The understanding of tinnitus has progressed considerably in the past decade, but the
details of the mechanisms that give rise to this phantom perception of sound without a …

Stochastic resonance controlled upregulation of internal noise after hearing loss as a putative cause of tinnitus-related neuronal hyperactivity

P Krauss, K Tziridis, C Metzner, A Schilling… - Frontiers in …, 2016 - frontiersin.org
Subjective tinnitus is generally assumed to be a consequence of hearing loss. In animal
studies it has been demonstrated that acoustic trauma induced cochlear damage can lead to …

Development of tinnitus‐related neuronal hyperactivity through homeostatic plasticity after hearing loss: a computational model

R Schaette, R Kempter - European Journal of Neuroscience, 2006 - Wiley Online Library
Tinnitus, the perception of a sound in the absence of acoustic stimulation, is often associated
with hearing loss. Animal studies indicate that hearing loss through cochlear damage can …

Special Issue “New Insights into Pathophysiology, Diagnosis and Treatment of Tinnitus”

P Cobo, M Cuesta - Brain Sciences, 2022 - mdpi.com
We are honoured to have been involved with Brain Sciences in the production of the Special
Issue “New Insights into Pathophysiology; Diagnosis and Treatment of Tinnitus” aiming to …