Drug repurposing in cancer therapy: influence of patient's genetic background in breast cancer treatment

R Rodrigues, D Duarte, N Vale - International journal of molecular …, 2022 - mdpi.com
Cancer is among the leading causes of death worldwide and it is estimated that in 2040
more than 29 million people will be diagnosed with some type of cancer. The most prevalent …

[HTML][HTML] Drugs repurposed: An advanced step towards the treatment of breast cancer and associated challenges

JA Malik, S Ahmed, B Jan, O Bender… - Biomedicine & …, 2022 - Elsevier
Breast cancer (BC) is mostly observed in women and is responsible for huge mortality in
women subjects globally. Due to the continued development of drug resistance and other …

Drug repurposing for breast cancer therapy: Old weapon for new battle

S Aggarwal, SS Verma, S Aggarwal… - Seminars in cancer biology, 2021 - Elsevier
Despite tremendous resources being invested in prevention and treatment, breast cancer
remains a leading cause of cancer deaths in women globally. The available treatment …

Understanding breast cancer: From conventional therapies to repurposed drugs

B Costa, I Amorim, F Gärtner, N Vale - European Journal of Pharmaceutical …, 2020 - Elsevier
Breast cancer is the most common cancer among women and is considered a developed
country disease. Moreover, is a heterogenous disease, existing different types and stages of …

Pathway-based drug repositioning for breast cancer molecular subtypes

RA Mejía-Pedroza, J Espinal-Enríquez… - Frontiers in …, 2018 - frontiersin.org
Breast cancer is a major public health problem which treatment needs new pharmacological
options. In the last decades, during the postgenomic era new theoretical and technological …

Drug repurposing for triple-negative breast cancer

M Ávalos-Moreno, A López-Tejada… - Journal of Personalized …, 2020 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer which
presents a high rate of relapse, metastasis, and mortality. Nowadays, the absence of …

Drug repurposing—an emerging strategy in cancer therapeutics

KS Turabi, A Deshmukh, S Paul, D Swami… - Naunyn-Schmiedeberg's …, 2022 - Springer
Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

Study of new therapeutic strategies to combat breast cancer using drug combinations

A Correia, D Silva, A Correia, M Vilanova, F Gärtner… - Biomolecules, 2018 - mdpi.com
Cancer is a disease that affects and kills millions of people worldwide. Breast cancer,
especially, has a high incidence and mortality, and is challenging to treat. Due to its high …

Drug repurposing: re-inventing therapies for cancer without re-entering the development pipeline—a review

S Siddiqui, AJ Deshmukh, P Mudaliar… - Journal of the Egyptian …, 2022 - Springer
While majority of the current treatment approaches for cancer remain expensive and are
associated with several side effects, development of new treatment modalities takes a …

Drug combination and repurposing for cancer therapy: the example of breast cancer

AS Correia, F Gärtner, N Vale - Heliyon, 2021 - cell.com
Cancer is a set of extremely complex diseases, which are increasingly prominent today, as it
affects and kills millions of people worldwide, being the subject of intense study both in its …