Peroxisome degradation, known as pexophagy, is essential for eliminating surplus and
dysfunctional peroxisomes, with dysregulation linked to various diseases. Previous research …

Peroxisomes are rapidly degraded during amino acid and oxygen deprivation by a type of
selective autophagy called pexophagy. However, how damaged peroxisomes are detected …

Autophagy is an intracellular degradation pathway for large protein aggregates and
damaged organelles. Recent studies have indicated that autophagy targets cargoes through …

Peroxisomes are highly plastic organelles that are involved in several metabolic processes,
including fatty acid oxidation, ether lipid synthesis and redox homeostasis. Their abundance …

Peroxisomes are degraded by a selective type of autophagy known as pexophagy. Several
different types of pexophagy have been reported in mammalian cells. However, the …

Peroxisomes are ubiquitous and highly dynamic organelles that play a central role in the
metabolism of lipids and reactive oxygen species. The importance of peroxisomal …

Protein ubiquitylation in mammals is known to trigger selective autophagy of peroxisomes
through a process termed pexophagy. The physiological peroxisomal target for pexophagy …

Peroxisomes are metabolic organelles necessary for anabolic and catabolic lipid reactions
whose numbers are highly dynamic based on the metabolic need of the cells. One …

Peroxisomes are organelles with key roles in metabolism including long-chain fatty acid
production. Their metabolic functions overlap and interconnect with those of mitochondria …

Peroxisomes play essential roles in diverse cellular metabolism functions, and their dynamic
homeostasis is maintained through the coordination of peroxisome biogenesis and turnover …