Abstract Interferon-γ (IFN-γ)-induced protein 10 (IP-10 or CXCL-10) is a chemokine involved
in trafficking immune cells to inflammatory sites. Numerous studies have reported …

Abstract HIV-1-infected subjects, despite control of viral replication with ART, have an
altered immune cytokine/chemokine milieu. Changes in systemic cytokines and chemokines …

Chemokines play critical roles in HIV-1 infection, serving both to modulate viral replication
and to recruit target cells to sites of infection. Interferon-γ-inducible protein 10 (IP …

Cytokines play key roles in modulating disease progression in simian immunodeficiency
virus/human immunodeficiency virus (SIV/HIV) infection. There are a few studies on the …

Objective: To study the cytokine/chemokine profiles in response to HIV-1 viremia, and
elucidate the pathways leading to HIV-1-induced inflammation. Design/methods: Plasma …

Elevated blood CXCL10/IP-10 levels during primary HIV-1 infection (PHI) were described as
an independent marker of rapid disease onset, more robust than peak viremia or CD4 cell …

Interferon-γ-inducible protein (IP-10 or CXCL10) is a potent chemoattractant and has been
suggested to enhance retrovirus infection and mediate neuronal injury. In order to assess …

A major barrier to HIV eradication is the persistence of viral reservoirs. Resting CD4+ T cells
are thought to be one of the major viral reservoirs, However, the underlying mechanism …

T cell activation levels, viral load and CD4+ T cell counts at early stages of HIV-1 infection
are predictive of the rate of progression towards AIDS. We evaluated whether the …

In HIV-infected patients, increased levels of IL-10, mainly produced by virally infected
monocytes, were reported to be associated with impaired cell-mediated immune responses …