The IgA isotype of anti-β2 glycoprotein I antibodies recognizes epitopes in domains 3, 4, and 5 that are located in a lateral zone of the molecule (L-Shaped)
Background: Antiphospholipid syndrome (APS) is characterized by thrombosis and/or
pregnancy morbidity with presence of anti-phospholipid antibodies (aPL). The APS …
pregnancy morbidity with presence of anti-phospholipid antibodies (aPL). The APS …
The weight of IgA anti-β2glycoprotein I in the antiphospholipid syndrome pathogenesis: closing the gap of seronegative antiphospholipid syndrome
O Cabrera-Marante, E Rodríguez de Frías… - International Journal of …, 2020 - mdpi.com
The specific value of IgA Anti-β2glycoprotein I antibodies (aB2GP1) in the diagnosis and
management of antiphospholipid syndrome (APS) is still controversial and a matter of active …
management of antiphospholipid syndrome (APS) is still controversial and a matter of active …
Antiphospholipid antibodies to domain I of beta-2-glycoprotein I show different subclass predominance in comparison to antibodies to whole beta-2-glycoprotein I
T McDonnell, B Artim-Esen, C Wincup… - Frontiers in …, 2018 - frontiersin.org
Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome
(APS), are a heterogeneous group of autoantibodies raised against circulating blood …
(APS), are a heterogeneous group of autoantibodies raised against circulating blood …
Antiphospholipid syndrome and IgA anti-beta2-glycoprotein I antibodies: when Cinderella becomes a princess
IgA anti-beta2-glycoprotein I (IgA-aB2GPI) antibodies are currently not included as a
laboratory criterion of antiphospholipid syndrome (APS). In the 13th International Congress …
laboratory criterion of antiphospholipid syndrome (APS). In the 13th International Congress …
New tests to detect antiphospholipid antibodies: anti-domain I beta-2-glycoprotein-I antibodies
CB Chighizola, M Gerosa, PL Meroni - Current rheumatology reports, 2014 - Springer
Abstract Beta-2 glycoprotein I (β 2 GPI) is the main antigenic target for antiphospholipid
antibodies (aPL), the serological markers of antiphospholipid syndrome (APS). Domain I (DI) …
antibodies (aPL), the serological markers of antiphospholipid syndrome (APS). Domain I (DI) …
Beyond thrombosis: Anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome
CB Chighizola, F Pregnolato, L Andreoli, C Bodio… - Journal of …, 2018 - Elsevier
Antibodies against β2 glycoprotein I (anti-β2GPI) have been identified as the main
pathogenic autoantibody subset in anti-phospholipid syndrome (APS); the most relevant …
pathogenic autoantibody subset in anti-phospholipid syndrome (APS); the most relevant …
Variability in exposure of epitope G40-R43 of domain i in commercial anti-beta2-glycoprotein I IgG ELISAs
L Pelkmans, H Kelchtermans, PG de Groot, S Zuily… - PloS one, 2013 - journals.plos.org
Background A major problem for diagnosing the antiphospholipid syndrome (APS) is the
high variability between commercial anti-β2glycoprotein I (β2GPI) assays. Predominantly …
high variability between commercial anti-β2glycoprotein I (β2GPI) assays. Predominantly …
Incidence of thromboembolic events in asymptomatic carriers of IgA anti ß2 glycoprotein-I antibodies
C Tortosa, O Cabrera-Marante, M Serrano… - PLoS …, 2017 - journals.plos.org
Background The antiphospholipid syndrome (APS) is defined by simultaneous presence of
vascular clinical events and antiphospholipid antibodies (aPL). The aPL considered as …
vascular clinical events and antiphospholipid antibodies (aPL). The aPL considered as …
Circulating immune complexes of IgA bound to beta 2 glycoprotein are strongly associated with the occurrence of acute thrombotic events
Aim: Antiphospholipid syndrome (APS) is characterized by recurrent thrombosis and/or
gestational morbidity in patients with antiphospholipid autoantibodies (aPL). Over recent …
gestational morbidity in patients with antiphospholipid autoantibodies (aPL). Over recent …
Anti-Beta 2-glycoprotein I antibody isotype and IgG subclass in antiphospholipid syndrome patients
J Guerin, E Casey, C Feighery, J Jackson - Autoimmunity, 1999 - Taylor & Francis
Beta 2-glycoprotein I (β2-GPI) is an antigenic target recognised by antiphospholipid
antibodies found in association with the antiphospholipid syndrome (APS). In this study, the …
antibodies found in association with the antiphospholipid syndrome (APS). In this study, the …