Urolithiasis affects around 10% of the US population with an increasing rate of prevalence,
recurrence and penetrance. The causes for the formation of most urinary calculi remain …

Kidney stone disease is a polygenic and multifactorial disorder with a worldwide distribution,
and its incidence and prevalence are increasing. Although significant progress has been …

Urine proteins are thought to control calcium oxalate stone formation, but over 1000 proteins
have been reported in stone matrix obscuring their relative importance. Proteins critical to …

Kidney stones are concretions of different mineral salts mixed with an organic matrix that
form in the upper urinary tract. As a stone moves from the kidney to the ureter, it can present …

Nephrolithiasis is a common disorder that accounts for significant cost, morbidity, and loss of
work. There is a one in eight lifetime chance of being diagnosed with urinary stones …

Introduction Main problems of kidney stone disease are its increasing prevalence and high
recurrence rate after calculi removal in almost all areas around the globe. Despite enormous …

Background Urolithiasis is a growing issue globally, but it is heterogeneous, with a different
epidemiology and pathophysiology for each different stone composition. Objective The …

Calcium oxalate urolithiasis is a common and painful condition in people. The pathogenesis
of this disease is complex and poorly understood. Laboratory animal and in vitro studies …

Calcium-based kidney stone disease is a highly prevalent and morbid condition, with an
often complicated and multifactorial aetiology. An abundance of research on the role of …

The presence and role of heavy metals in urinary stones is debated. We investigated the
distribution of trace heavy metals in 78 calculi of well-defined composition by means of …