[HTML][HTML] Investigation of polycaprolactone for bone tissue engineering scaffolds: In vitro degradation and biological studies

Y Hou, W Wang, P Bartolo - Materials & Design, 2022 - Elsevier
Polycaprolactone (PCL) is one of the most recognized polymeric materials used for bone
tissue engineering scaffold fabrication. This study aims to evaluate the effects of the …

The pore size of polycaprolactone scaffolds has limited influence on bone regeneration in an in vivo model

SMM Roosa, JM Kemppainen, EN Moffitt… - … Research Part A: An …, 2010 - Wiley Online Library
Bone tissue engineering scaffolds should be designed to optimize mass transport, cell
migration, and mechanical integrity to facilitate and enhance new bone growth. Although …

Polycaprolactone as biomaterial for bone scaffolds: Review of literature

R Dwivedi, S Kumar, R Pandey, A Mahajan… - Journal of oral biology …, 2020 - Elsevier
Bone tissue engineering using polymer based scaffolds have been studied a lot in last
decades. Considering the qualities of all the polymers desired to be used as scaffolds …

Development of polycaprolactone porous scaffolds by combining solvent casting, particulate leaching, and polymer leaching techniques for bone tissue engineering

N Thadavirul, P Pavasant… - Journal of biomedical …, 2014 - Wiley Online Library
Sodium chloride and polyethylene glycol (PEG) were used as water‐soluble porogens for
the formation of porous polycaprolactone (PCL) scaffolds. The main purpose was to prepare …

Polycaprolactone scaffolds and hydroxyapatite/polycaprolactone composite scaffolds for bone tissue engineering

N Sultana, T Hayat Khan - Journal of Bionanoscience, 2013 - ingentaconnect.com
Scaffolds fabricated from biodegradable polymers and bioactive materials together with
living cells are often used in tissue engineering. This paper reports the thermally induced …

Effect of Polycaprolactone Scaffold Permeability on Bone Regeneration In Vivo

AG Mitsak, JM Kemppainen, MT Harris… - … Engineering Part A, 2011 - liebertpub.com
Successful bone tissue engineering depends on the scaffold's ability to allow nutrient
diffusion to and waste removal from the regeneration site, as well as provide an appropriate …

Hybrid polycaprolactone/polyethylene oxide scaffolds with tunable fiber surface morphology, improved hydrophilicity and biodegradability for bone tissue engineering …

KR Remya, S Chandran, S Mani, A John… - Journal of Biomaterials …, 2018 - Taylor & Francis
In the present study, we attempt to modify Polycaprolactone (PCL) by blending it with a water
soluble polymer Polyethyleneoxide (PEO) having two different molecular weights (Mv~ 1 …

Evaluation of polycaprolactone scaffold degradation for 6 months in vitro and in vivo

CXF Lam, DW Hutmacher, JT Schantz… - … Research Part A: An …, 2009 - Wiley Online Library
The use of polycaprolactone (PCL) as a biomaterial, especially in the fields of drug delivery
and tissue engineering, has enjoyed significant growth. Understanding how such a device …

[HTML][HTML] Bioactive and biodegradable polycaprolactone-based nanocomposite for bone repair applications

H Emadi, M Karevan, M Masoudi Rad, S Sadeghzade… - Polymers, 2023 - mdpi.com
This study investigated the relationship between the structure and mechanical properties of
polycaprolactone (PCL) nanocomposites reinforced with baghdadite, a newly introduced …

Polycaprolactone scaffolds for bone tissue engineering: effects of a calcium phosphate coating layer on osteogenic cells

C Choong, JT Triffitt, ZF Cui - Food and bioproducts processing, 2004 - Elsevier
Biodegradable polycaprolactone (PCL) scaffolds made by fused deposition modeling (FDM)
were coated with a layer of calcium phosphate using a biomimetic method and seeded with …