Synthetic implants are used to treat large bone defects that are often unable to regenerate,
for example those caused by osteoporosis. It is necessary that the materials used to …

The fabrication of a suitable scaffold material is one of the major challenges for bone tissue
engineering. Poly (lactic acid)(PLA) is one of the most favorable matrix materials in bone …

The major problem in bone tissue engineering is the development of scaffolds which can
simultaneously meet the requirements of porous structure, as well as have the ability to …

Background: In this study, scaffolds were fabricated using a desktop robot based rapid
prototyping (DRBRP) system that was developed in-house. Poly lactic acid (PLA) and …

Synthetic bone graft substitutes based on composites consisting of a polymer and a calcium-
phosphate (CaP) ceramic are developed with the aim to satisfy both mechanical and …

Implantation of bone substitutes is the treatment of choice for bone defects exceeding a
critical size, when self-healing becomes impossible. The use of 3D printing techniques …

Improvements in Tissue Engineering and Regenerative Medicine (TERM)–type
technologies have allowed the development of specific materials that, together with a better …

This paper exclusively describes the biocompatibility evaluation of biodegradable PLA–HA-
based composites as temporary bone scaffolds for bone tissue engineering in orthopaedic …

The incorporation of ceramic additives is the most commonly used strategy to improve the
biofunctionality of polymer-based scaffolds intended for bone regeneration. By embedding …

Bone is the second most common connective tissue worldwide and more than four million
bone grafts or substitutes are used annually to treat bone defects. Due to the restrictions of …