The modulation of TRPV1 emerges as a promising strategy for dental pain management.
This study aimed to assess TRPV1 modulation in a human odontoblast-like cell model using …

Objectives Dental pain, which is the main reason for patients consulting dentists, is classified
as a public health concern. The study of cellular and molecular mechanisms contributing to …

Drug-induced gingival enlargement (GE) is a frequent adverse effect observed in patients
treated with anticonvulsant, immunosuppressant, and some antihypertensive medications …

Background: Transient Receptor Potential (TRP) channels are non-selective Ca2+
permeable channels with a wide and dynamic involvement in the perception of …

Dentinal hypersensitivity is a frequent reason for dental consultation, and its
pathophysiology has not been fully clarified. Previous findings have made it possible to …

Curcumin has diverse therapeutic effects, such as anti-inflammatory, anti-oxidant, anti-
cancer, and antimicrobial activities. The vanilloid moiety of curcumin is considered important …

The vanilloid receptor TRPV1 is now recognized as a molecular integrator of painful stimuli
ranging from noxious heat to endovanilloids in inflammation. Pharmacological blockade of …

Orthodontic pain that is induced by tooth movement is an important sequela of orthodontic
treatment and has a significant effect on patient quality of life. Studies have shown that the …

The vanilloid receptor (TRPV1) has attracted a great expectation in pain therapeutics for the
treatment of chronic inflammatory conditions. As a result, several drug discovery …

Chronic pain management poses a formidable challenge to healthcare, exacerbated by
current analgesic options' limitations and adverse effects. Transient receptor potential …