Parkinson's disease (PD) is a progressive neurological disorder associated with the loss of
dopaminergic neurons (DNs) in the substantia nigra and the widespread accumulation of α …

Despite Parkinson's Disease (PD) being the second most common neurodegenerative
disease, treatment options are limited. Consequently, there is an urgent need to identify and …

The nematode Caenorhabditis elegans is a widely adopted model organism for studying
various neurobiological processes at the molecular and cellular level in vivo. With a small …

Human movement disorders represent a significant and unresolved societal burden. Among
these, the most prevalent is Parkinson's disease (PD), a disorder afflicting millions …

Parkinson's disease (PD) is a neurodegenerative disorder with symptoms that progressively
worsen with age. Pathologically, PD is characterized by the aggregation of α-synuclein in …

It has been over forty years since dopamine neuron degeneration in the substantia nigra
and Lewy body formation within surviving cells were described as the pathological …

Parkinson's disease (PD) is an age‐related movement disorder resulting, in part, from
selective loss of dopaminergic neurons. Both invertebrate and mammalian models have …

Protein misfolding and aggregation are key pathological features observed in numerous
neurodegenerative diseases, including the misfolding of α-synuclein (α-syn) in Parkinson's …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-
motor symptoms and the selective loss of dopaminergic neurons. The etiology of idiopathic …

Abstract Three-dimensional (3D) in vitro culture systems using human induced pluripotent
stem cells (hiPSCs) are useful tools to model neurodegenerative disease biology in …