Patients with familial pulmonary fibrosis represent a subset of patients with pulmonary
fibrosis in whom inherited gene variation predisposes them to disease development. In the …

There has been increasing recognition that genetic factors play important roles in both
sporadic and familial cases of idiopathic pulmonary fibrosis (IPF)(1). Current data indicate …

Background Idiopathic pulmonary fibrosis, the most common form of idiopathic interstitial
pneumonia, is characterized by progressive, irreversible scarring of the lung parenchyma …

The inherited risk for pulmonary fibrosis is substantial, and recent data suggest that genetic
risk for familial and sporadic forms of the disease are similar. Further characterizing this …

Genetic predisposition to pulmonary fibrosis has been confirmed by the discovery of several
gene mutations that cause pulmonary fibrosis. Although genetic sequencing of familial …

Pulmonary fibrosis comprises a wide range of fibrotic lung diseases with unknown
pathogenesis and poor prognosis. Familial pulmonary fibrosis (FPF) represents a unique …

Idiopathic pulmonary fibrosis (IPF) is a chronic, rare progressive lung disease, characterized
by lung scarring and the irreversible loss of lung function. Two anti-fibrotic drugs, nintedanib …

Pulmonary fibrosis refers to the development of diffuse parenchymal abnormalities in the
lung that cause dyspnea, cough, hypoxemia, and impair gas exchange, ultimately leading to …

Recent advances in the genetics of idiopathic pulmonary fibr... : Current Opinion in Pulmonary
Medicine Recent advances in the genetics of idiopathic pulmonary fibrosis : Current Opinion …

Introduction: Many forms of interstitial lung disease (ILD) can progress to extensive fibrosis
and respiratory failure. Idiopathic pulmonary fibrosis (IPF), which generally has a poor …