Pregnant ewes were fed either a 50% nutrient‐restricted (NR; n= 8) or a control 100%(C; n=
8) diet from day 28 to day 78 of gestation (dGA; term= 150 dGA). Lambs were born naturally …

Inadequate nutrition compromises fetal development and poses long-term health risks for
the offspring, even without decreased birth weight. The present study sought to 1) establish …

Studies have shown that the risk of hypertension in adulthood can be affected by the in utero
environment. It is established that hypertension is linked to compromised kidney function …

Placental weight is a primary factor determining size at birth in many species. In sheep,
placental weight peaks at approximately mid-gestation, with structural remodelling occurring …

The prenatal nutritional environment influences the subsequent risk of hypertension in
adulthood. Animal studies have used, generally, the rat as a model species to illustrate the …

Reduced nephron endowment is associated with development of renal and cardiovascular
disease. We hypothesized this may be attributable to impaired sodium homoeostasis by the …

Early gestation is critical for placentomal growth, differentiation, and vascularization, as well
as fetal organogenesis. The fetal origins of adult disease hypothesis proposes that …

Maternal water restriction and the accompanying dehydration-induced anorexia may induce
long-term physiological changes in offspring. We determined the impact of prenatal …

We have investigated the effect of a 50% reduction in maternal nutrient intake during the last
30 days of pregnancy on arterial blood pressure and on arterial blood pressure responses to …

Previous studies in rodents and sheep show that maternal nutrient restriction during
pregnancy alters fetal renal development. To date, no studies using fetal baboon RNA with …