Background & Aims Guidelines for initiating colorectal cancer (CRC) screening are based
on family history but do not consider lifestyle, environmental, or genetic risk factors. We …

Background The incidence of colorectal cancer (CRC) among individuals aged younger
than 50 years has been increasing. As screening guidelines lower the recommended age of …

Background & Aims Risk for colorectal cancer (CRC) can be greatly reduced through
screening. To aid in the development of screening strategies, we refined models designed to …

Current colorectal cancer (CRC) screening recommendations take a “one-size-fits-all”
approach using age as the major criterion to initiate screening. Precision screening that …

Background Initiating screening at an earlier age based on cancer family history is one of
the primary recommended strategies for the prevention and detection of early‐onset …

Colorectal cancer is the second leading cause of cancer-related death in Europe and the
United States. Survival is strongly related to stage at diagnosis and population-based …

Background & Aims Estimates of absolute risk of colorectal cancer (CRC) are needed to
facilitate communication and better inform the public about the potentials and limits of cancer …

Background & Aims A valid risk prediction model for colorectal neoplasia would allow
patients to be screened for colorectal cancer (CRC) on the basis of risk. We performed a …

However, CRC incidence and mortality have been decreasing over the past 4 decades, and
screening has contributed substantially to these gains. 2–4 Screening aims to identify …

Purpose Given the high incidence of colorectal cancer (CRC), and the availability of
procedures that can detect disease and remove precancerous lesions, there is a need for a …