The neural correlates of optimal states for signal detection task performance are largely
unknown. One hypothesis holds that optimal states exhibit tonically depolarized cortical …

Perceptual decision-making is highly dependent on the momentary arousal state of the
brain, which fluctuates over time on a scale of hours, minutes, and even seconds. The …

Cortical excitability is assumed to depend on cortical arousal level in an inverted U-shaped
fashion: Largest (optimal) excitability is usually associated with medium levels of arousal. It …

Perceiving an external stimulus depends not only on the physical features of the stimulus,
but also fundamentally on the current state of neuronal excitability, indexed by the power of …

Although oscillations in membrane potential are a prominent feature of sensory, motor, and
cognitive function, their precise role in signal processing remains elusive. Here we show …

Instantaneous brain states have consequences for our sensation, perception, and
behaviour. Fluctuations in arousal and neural desynchronization likely pose perceptually …

Estimating cognitive or affective state from neurophysiological signals and designing
applications that make use of this information requires expertise in many disciplines such as …

Cortical sensory processing is modulated by behavioral and cognitive states. How this
modulation is achieved by changing synaptic circuits remains largely unknown. In awake …

The ability to process and respond to external input is critical for adaptive behavior. Why,
then, do neural and behavioral responses vary across repeated presentations of the same …

How do cortical neurons represent the acoustic environment? This question is often
addressed by probing with simple stimuli such as clicks or tone pips. Such stimuli have the …