Activation of natural killer cells during acute infection with hepatitis C virus
B Amadei, S Urbani, A Cazaly, P Fisicaro, A Zerbini… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: Natural killer (NK) cells are essential early after infection, not only
for viral containment but also for timely and efficient induction of adaptive responses. An …
for viral containment but also for timely and efficient induction of adaptive responses. An …
Immunomodulation of the natural killer cell phenotype and response during HCV infection
Hepatitis C virus (HCV) infection develops into chronic hepatitis in over two-thirds of acute
infections. While current treatments with direct-acting antivirals (DAAs) achieve HCV …
infections. While current treatments with direct-acting antivirals (DAAs) achieve HCV …
[HTML][HTML] Natural killer cells in hepatitis C: Current progress
JC Yoon, CM Yang, Y Song, JM Lee - World journal of …, 2016 - ncbi.nlm.nih.gov
Patients infected with the hepatitis C virus (HCV) are characterized by a high incidence of
chronic infection, which results in chronic hepatitis, liver cirrhosis, and hepatocellular …
chronic infection, which results in chronic hepatitis, liver cirrhosis, and hepatocellular …
The paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment
Objective There is evidence that natural killer (NK) cells help control persistent viral
infections including hepatitis C virus (HCV). The phenotype and function of blood and …
infections including hepatitis C virus (HCV). The phenotype and function of blood and …
Natural killer cells in viral hepatitis: facts and controversies
MU Mondelli, S Varchetta… - European journal of …, 2010 - Wiley Online Library
Eur J Clin Invest 2010; 40 (9): 851–863 Abstract Background Hepatitis B virus (HBV) and
hepatitis C virus (HCV) are major human hepatotropic pathogens responsible for a large …
hepatitis C virus (HCV) are major human hepatotropic pathogens responsible for a large …
Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections
B Oliviero, S Varchetta, E Paudice, G Michelone… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: The phenotypic and functional characteristics of natural killer (NK)
cells in chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are …
cells in chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are …
Phenotypic and Functional Changes of Cytotoxic CD56pos Natural T Cells Determine Outcome of Acute Hepatitis C Virus Infection
L Golden-Mason, N Castelblanco, C O'Farrelly… - Journal of …, 2007 - Am Soc Microbiol
Innate CD56pos natural killer (NK) and natural T (NT) cells comprise important hepatic
antiviral effector lymphocytes whose activity is fine-tuned through surface NK receptors …
antiviral effector lymphocytes whose activity is fine-tuned through surface NK receptors …
Increased degranulation of natural killer cells during acute HCV correlates with the magnitude of virus-specific T cell responses
S Pelletier, C Drouin, N Bédard, SI Khakoo… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Natural killer (NK) cells provide early defense against viral
infections by killing infected cells and producing cytokines that inhibit viral replication. NK …
infections by killing infected cells and producing cytokines that inhibit viral replication. NK …
Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C
BACKGROUND & AIMS: Mathematical modeling of hepatitis C virus (HCV) kinetics indicated
that cellular immune responses contribute to interferon (IFN)-induced clearance of HCV. We …
that cellular immune responses contribute to interferon (IFN)-induced clearance of HCV. We …
Natural killer cells: multifaceted players with key roles in hepatitis C immunity
L Golden‐Mason, HR Rosen - Immunological reviews, 2013 - Wiley Online Library
Natural killer cells (NK s) are involved in every stage of hepatitis C viral (HCV) infection, from
protection against HCV acquisition and resolution in the acute phase to treatment‐induced …
protection against HCV acquisition and resolution in the acute phase to treatment‐induced …